A Cytosine Methytransferase Modulates the Cell Envelope Stress Response in the Cholera Pathogen

Michael C. Chao; Shijia Zhu; Satoshi Kimura; Brigid M. Davis; Eric E. Schadt; Gang Fang; Matthew K. Waldor

doi:10.1371/journal.pgen.1005666

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Peer-reviewed

Research Article

A Cytosine Methytransferase Modulates the Cell Envelope Stress Response in the Cholera Pathogen

Michael C. Chao,

Affiliations Division of Infectious Disease, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America
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Shijia Zhu,

Affiliation Department of Genetics and Genomic Sciences, Institute for Genomics and Multi-scale Biology, Mount Sinai School of Medicine, New York, New York, United States of America
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Satoshi Kimura,

Affiliations Division of Infectious Disease, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Brigid M. Davis,

Affiliations Division of Infectious Disease, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America
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Eric E. Schadt,

Affiliation Howard Hughes Medical Institute, Boston, Massachusetts, United States of America
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Gang Fang ,

* E-mail: gang.fang@mssm.edu (GF); mwaldor@research.bwh.harvard.edu (MKW)

Affiliation Department of Genetics and Genomic Sciences, Institute for Genomics and Multi-scale Biology, Mount Sinai School of Medicine, New York, New York, United States of America
⨯
Matthew K. Waldor

* E-mail: gang.fang@mssm.edu (GF); mwaldor@research.bwh.harvard.edu (MKW)

Affiliations Division of Infectious Disease, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

A Cytosine Methytransferase Modulates the Cell Envelope Stress Response in the Cholera Pathogen

Michael C. Chao,
Shijia Zhu,
Satoshi Kimura,
Brigid M. Davis,
Eric E. Schadt,
Gang Fang,
Matthew K. Waldor

Published: November 20, 2015
https://doi.org/10.1371/journal.pgen.1005666

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Vibrio cholerae
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DNA methylation
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Gene expression
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Methylation
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Outer membrane proteins
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Genomics
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Cytosine
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Sequence motif analysis
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