A Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures

Open Access

Peer-reviewed

Research Article

Yuichi Shiraishi ,

* E-mail: yshira@hgc.jp (YS); mstephens@uchicago.edu (MS)

Affiliation Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
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Georg Tremmel,

Affiliation Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
⨯
Satoru Miyano,

Affiliation Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
⨯
Matthew Stephens

* E-mail: yshira@hgc.jp (YS); mstephens@uchicago.edu (MS)

Affiliations Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America, Department of Statistics, University of Chicago, Chicago, Illinois, United States of America
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Substitution mutation
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Lung and intrathoracic tumors
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Somatic mutation
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Cancers and neoplasms
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Mutation detection
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