Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development

Yu Hasegawa; Deanne Taylor; Dmitry A. Ovchinnikov; Ernst J. Wolvetang; Laurence de Torrenté; Jessica C. Mar

doi:10.1371/journal.pgen.1005428

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Open Access

Peer-reviewed

Research Article

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development

Yu Hasegawa,

Affiliations Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America, Division of Life Science, Graduate School of Life Science, Hokkaido University, Sapporo, Hokkaido, Japan
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Deanne Taylor,

Current Address: Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Affiliations RMANJ Reproductive Medicine Associates of New Jersey, Morristown, New Jersey, United States of America, Division of Reproductive Endocrinology, Department of Obstetrics, Gynecology, and Reproductive Science, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey, United States of America
⨯
Dmitry A. Ovchinnikov,

Affiliation Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Queensland, Australia
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Ernst J. Wolvetang,

Affiliation Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Queensland, Australia
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Laurence de Torrenté,

Affiliation Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America
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Jessica C. Mar

* E-mail: jessica.mar@einstein.yu.edu

Affiliations Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, United States of America
⨯

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development

Yu Hasegawa,
Deanne Taylor,
Dmitry A. Ovchinnikov,
Ernst J. Wolvetang,
Laurence de Torrenté,
Jessica C. Mar

Published: August 19, 2015
https://doi.org/10.1371/journal.pgen.1005428

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Gene expression
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Blastocysts
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Gene regulation
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Embryos
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Transcriptome analysis
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Pluripotency
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DNA transcription
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Transcriptional control
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