Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2

Blair B. Madison; Arjun N. Jeganathan; Rei Mizuno; Monte M. Winslow; Antoni Castells; Miriam Cuatrecasas; Anil K. Rustgi

doi:10.1371/journal.pgen.1005408

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Peer-reviewed

Research Article

Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2

Blair B. Madison,

Affiliations Division of Gastroenterology, Washington University School of Medicine, Saint Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, Saint Louis, Missouri, United States of America
⨯
Arjun N. Jeganathan,

Affiliations Division of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Rei Mizuno,

Affiliations Division of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Monte M. Winslow,

Affiliation Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Antoni Castells,

Affiliation Gastroenterology Department, Hospital Clínic, CIBERehd, IDIBAPS, Barcelona, Catalonia, Spain
⨯
Miriam Cuatrecasas,

Affiliation Department of Pathology, Pharmacology and Microbiology, Hospital Clínic, CDB, University of Barcelona, Barcelona, Catalonia, Spain
⨯
Anil K. Rustgi

* E-mail: anil2@mail.med.upenn.edu

Affiliations Division of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯

Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2

Blair B. Madison,
Arjun N. Jeganathan,
Rei Mizuno,
Monte M. Winslow,
Antoni Castells,
Miriam Cuatrecasas,
Anil K. Rustgi

Published: August 5, 2015
https://doi.org/10.1371/journal.pgen.1005408

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