Emergence, Retention and Selection: A Trilogy of Origination for Functional De Novo Proteins from Ancestral LncRNAs in Primates

• Jia-Yu Chen ,

  Contributed equally to this work with: Jia-Yu Chen, Qing Sunny Shen, Wei-Zhen Zhou

  Affiliation Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China

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• Qing Sunny Shen ,

  Contributed equally to this work with: Jia-Yu Chen, Qing Sunny Shen, Wei-Zhen Zhou

  Affiliation Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China

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• Wei-Zhen Zhou ,

  Contributed equally to this work with: Jia-Yu Chen, Qing Sunny Shen, Wei-Zhen Zhou

  Affiliation Center for Bioinformatics, National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing, China

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• Jiguang Peng,

  Affiliation Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China

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• Bin Z. He,

  Affiliation FAS Center for Systems Biology & Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts, United States of America

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• Yumei Li,

  Affiliation Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China

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• Chu-Jun Liu,

  Affiliation Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China

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• Xuke Luan,

  Affiliations Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China, Peking-Tsinghua Center for Life Sciences, Beijing, China

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• Wanqiu Ding,

  Affiliation Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China

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• Shuxian Li,

  Affiliation Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China

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• Chunyan Chen,

  Affiliation Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

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• Bertrand Chin-Ming Tan,

  Affiliation Molecular Medicine Research Center, Chang Gung University, Tao-Yuan, Taiwan

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• Yong E. Zhang,

  Affiliation Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

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• Aibin He ,

  * E-mail: ahe@pku.edu.cn (AH); chuanyunli@pku.edu.cn (CYL)

  Affiliations Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China, Peking-Tsinghua Center for Life Sciences, Beijing, China

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• Chuan-Yun Li

  * E-mail: ahe@pku.edu.cn (AH); chuanyunli@pku.edu.cn (CYL)

  Affiliation Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China

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