Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice

Gerhard Sengle; Valerie Carlberg; Sara F. Tufa; Noe L. Charbonneau; Silvia Smaldone; Eric J. Carlson; Francesco Ramirez; Douglas R. Keene; Lynn Y. Sakai

doi:10.1371/journal.pgen.1005340

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Peer-reviewed

Research Article

Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice

Gerhard Sengle,

Current address: Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany and Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.

Affiliations Department of Biochemistry & Molecular Biology, Oregon Health & Science University, Portland, Oregon, United States of America, Shriners Hospital for Children, Portland, Oregon, United States of America
⨯
Valerie Carlberg,

Affiliations Department of Biochemistry & Molecular Biology, Oregon Health & Science University, Portland, Oregon, United States of America, Shriners Hospital for Children, Portland, Oregon, United States of America
⨯
Sara F. Tufa,

Affiliation Shriners Hospital for Children, Portland, Oregon, United States of America
⨯
Noe L. Charbonneau,

Affiliation Shriners Hospital for Children, Portland, Oregon, United States of America
⨯
Silvia Smaldone,

Affiliation Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America
⨯
Eric J. Carlson,

Affiliation Shriners Hospital for Children, Portland, Oregon, United States of America
⨯
Francesco Ramirez,

Affiliation Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America
⨯
Douglas R. Keene,

Affiliation Shriners Hospital for Children, Portland, Oregon, United States of America
⨯
Lynn Y. Sakai

* E-mail: lys@shcc.org

Affiliations Department of Biochemistry & Molecular Biology, Oregon Health & Science University, Portland, Oregon, United States of America, Shriners Hospital for Children, Portland, Oregon, United States of America
⨯

Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice

Gerhard Sengle,
Valerie Carlberg,
Sara F. Tufa,
Noe L. Charbonneau,
Silvia Smaldone,
Eric J. Carlson,
Francesco Ramirez,
Douglas R. Keene,
Lynn Y. Sakai

Published: June 26, 2015
https://doi.org/10.1371/journal.pgen.1005340

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BMP signaling
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Forearms
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Skeletal muscles
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Fats
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Muscle contraction
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Muscular dystrophies
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Muscle differentiation
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Heterozygosity
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