Monoallelic Loss of the Imprinted Gene Grb10 Promotes Tumor Formation in Irradiated Nf1+/- Mice

Open Access

Peer-reviewed

Research Article

Monoallelic Loss of the Imprinted Gene Grb10 Promotes Tumor Formation in Irradiated Nf1^+/- Mice

Rana Mroue,

Affiliation Department of Radiation Oncology, University of California, San Francisco, San Francisco, California, United States of America
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Brian Huang,

Affiliation Department of Radiation Oncology, University of California, San Francisco, San Francisco, California, United States of America
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Steve Braunstein,

Affiliation Department of Radiation Oncology, University of California, San Francisco, San Francisco, California, United States of America
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Ari J. Firestone,

Affiliation Department of Pediatrics, University of California, San Francisco, San Francisco, California, United States of America
⨯
Jean L. Nakamura

Affiliation Department of Radiation Oncology, University of California, San Francisco, San Francisco, California, United States of America
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Neurofibromatosis type 1
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Malignant tumors
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Mouse models
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Ras signaling
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Cancers and neoplasms
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Insulin
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MAPK signaling cascades
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Carcinogenesis
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