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Open Access
Peer-reviewed
Research Article
Mitochondrial Dysfunction Reveals the Role of mRNA Poly(A) Tail Regulation in Oculopharyngeal Muscular Dystrophy Pathogenesis
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Aymeric Chartier ,
¶‡ AC and PK contributed equally to this work. CT and MS also contributed equally to this work.
Affiliation mRNA Regulation and Development, Institut de Génétique Humaine, CNRS UPR1142, Montpellier, France
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Pierre Klein ,
¶‡ AC and PK contributed equally to this work. CT and MS also contributed equally to this work.
Affiliation Sorbonne Universités, UPMC Univ Paris 06, UM76, INSERM UMRS974, CNRS FRE3617, Center for Research in Myology, Paris, France
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Stéphanie Pierson,
Affiliation mRNA Regulation and Development, Institut de Génétique Humaine, CNRS UPR1142, Montpellier, France
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Nicolas Barbezier,
Affiliation mRNA Regulation and Development, Institut de Génétique Humaine, CNRS UPR1142, Montpellier, France
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Teresa Gidaro,
Affiliation Sorbonne Universités, UPMC Univ Paris 06, UM76, INSERM UMRS974, CNRS FRE3617, Center for Research in Myology, Paris, France
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François Casas,
Affiliation INRA, UMR 866 Différenciation cellulaire et croissance, Montpellier, France
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Steven Carberry,
Affiliation Department of Biology, National University of Ireland, Maynooth, Ireland
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Paul Dowling,
Affiliation Department of Biology, National University of Ireland, Maynooth, Ireland
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Laurie Maynadier,
Affiliation mRNA Regulation and Development, Institut de Génétique Humaine, CNRS UPR1142, Montpellier, France
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Maëlle Bellec,
Affiliation mRNA Regulation and Development, Institut de Génétique Humaine, CNRS UPR1142, Montpellier, France
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Martine Oloko,
Affiliation Sorbonne Universités, UPMC Univ Paris 06, UM76, INSERM UMRS974, CNRS FRE3617, Center for Research in Myology, Paris, France
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Claude Jardel,
Affiliation Service de Biochimie Métabolique et Centre de Génétique moléculaire et chromosomique, INSERM U1016, Institut Cochin, CNRS UMR 8104, AP-HP, GHU Pitié-Salpêtrière, Paris, France
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Bodo Moritz,
Affiliation Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Halle, Germany
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George Dickson,
Affiliation School of Biological Sciences, Royal Holloway - University of London, Egham, Surrey, United Kingdom
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Vincent Mouly,
Affiliation Sorbonne Universités, UPMC Univ Paris 06, UM76, INSERM UMRS974, CNRS FRE3617, Center for Research in Myology, Paris, France
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Kay Ohlendieck,
Affiliation Department of Biology, National University of Ireland, Maynooth, Ireland
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Gillian Butler-Browne,
Affiliation Sorbonne Universités, UPMC Univ Paris 06, UM76, INSERM UMRS974, CNRS FRE3617, Center for Research in Myology, Paris, France
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Capucine Trollet ,
¶‡ AC and PK contributed equally to this work. CT and MS also contributed equally to this work.
Affiliation Sorbonne Universités, UPMC Univ Paris 06, UM76, INSERM UMRS974, CNRS FRE3617, Center for Research in Myology, Paris, France
⨯ - [ ... ],
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Martine Simonelig
* E-mail: Martine.Simonelig@igh.cnrs.fr
¶‡ AC and PK contributed equally to this work. CT and MS also contributed equally to this work.
Affiliation mRNA Regulation and Development, Institut de Génétique Humaine, CNRS UPR1142, Montpellier, France
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Mitochondrial Dysfunction Reveals the Role of mRNA Poly(A) Tail Regulation in Oculopharyngeal Muscular Dystrophy Pathogenesis
- Aymeric Chartier,
- Pierre Klein,
- Stéphanie Pierson,
- Nicolas Barbezier,
- Teresa Gidaro,
- François Casas,
- Steven Carberry,
- Paul Dowling,
- Laurie Maynadier,
- Maëlle Bellec
- Published: March 27, 2015
- https://doi.org/10.1371/journal.pgen.1005092