Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans

Angela Pyle; Gavin Hudson; Ian J. Wilson; Jonathan Coxhead; Tania Smertenko; Mary Herbert; Mauro Santibanez-Koref; Patrick F. Chinnery

doi:10.1371/journal.pgen.1005040

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Peer-reviewed

Research Article

Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans

Angela Pyle,

Affiliations Wellcome Trust Centre for Mitochondrial Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom, Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom
⨯
Gavin Hudson,

Affiliations Wellcome Trust Centre for Mitochondrial Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom, Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom
⨯
Ian J. Wilson,

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom
⨯
Jonathan Coxhead,

Affiliations Wellcome Trust Centre for Mitochondrial Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom, Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom
⨯
Tania Smertenko,

Affiliations Wellcome Trust Centre for Mitochondrial Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom, Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom
⨯
Mary Herbert,

Affiliations Wellcome Trust Centre for Mitochondrial Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom, Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom
⨯
Mauro Santibanez-Koref,

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom
⨯
Patrick F. Chinnery

* E-mail: patrick.chinnery@ncl.ac.uk

Affiliations Wellcome Trust Centre for Mitochondrial Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom, Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom
⨯

Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans

Angela Pyle,
Gavin Hudson,
Ian J. Wilson,
Jonathan Coxhead,
Tania Smertenko,
Mary Herbert,
Mauro Santibanez-Koref,
Patrick F. Chinnery

Published: May 14, 2015
https://doi.org/10.1371/journal.pgen.1005040

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