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Open Access
Peer-reviewed
Research Article
Tissue-Specific Effects of Genetic and Epigenetic Variation on Gene Regulation and Splicing
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Maria Gutierrez-Arcelus ,
Contributed equally to this work with: Maria Gutierrez-Arcelus, Halit Ongen, Tuuli Lappalainen, Stephen B. Montgomery
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland
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Halit Ongen ,
Contributed equally to this work with: Maria Gutierrez-Arcelus, Halit Ongen, Tuuli Lappalainen, Stephen B. Montgomery
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland
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Tuuli Lappalainen ,
Contributed equally to this work with: Maria Gutierrez-Arcelus, Halit Ongen, Tuuli Lappalainen, Stephen B. Montgomery
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland
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Stephen B. Montgomery ,
Contributed equally to this work with: Maria Gutierrez-Arcelus, Halit Ongen, Tuuli Lappalainen, Stephen B. Montgomery
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Departments of Pathology and Genetics, Stanford University, Stanford, California, United States of America
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Alfonso Buil,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland
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Alisa Yurovsky,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland
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Julien Bryois,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland
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Ismael Padioleau,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland
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Luciana Romano,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland
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Alexandra Planchon,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland
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Emilie Falconnet,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland
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Deborah Bielser,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland
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Maryline Gagnebin,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland
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Thomas Giger,
Affiliation Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
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Christelle Borel,
Affiliation Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
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Audrey Letourneau,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland
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Periklis Makrythanasis,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland
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Michel Guipponi,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland
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Corinne Gehrig,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland
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Stylianos E. Antonarakis ,
* E-mail: stylianos.antonarakis@unige.ch (SEA); Emmanouil.dermitzakis@unige.ch (ETD)
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland
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Emmanouil T. Dermitzakis
* E-mail: stylianos.antonarakis@unige.ch (SEA); Emmanouil.dermitzakis@unige.ch (ETD)
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland, Center of Excellence in Genomic Medicine Research, KingAbdulaziz University, Jeddah, Saudi Arabia
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Tissue-Specific Effects of Genetic and Epigenetic Variation on Gene Regulation and Splicing
- Maria Gutierrez-Arcelus,
- Halit Ongen,
- Tuuli Lappalainen,
- Stephen B. Montgomery,
- Alfonso Buil,
- Alisa Yurovsky,
- Julien Bryois,
- Ismael Padioleau,
- Luciana Romano,
- Alexandra Planchon
- Published: January 29, 2015
- https://doi.org/10.1371/journal.pgen.1004958