Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis

Mengcheng Luo; Jian Zhou; N. Adrian Leu; Carla M. Abreu; Jianle Wang; Montserrat C. Anguera; Dirk G. de Rooij; Maria Jasin; P. Jeremy Wang

doi:10.1371/journal.pgen.1004954

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Research Article

Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis

Mengcheng Luo,

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Jian Zhou,

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
N. Adrian Leu,

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Carla M. Abreu,

Affiliation Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
⨯
Jianle Wang,

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Montserrat C. Anguera,

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Dirk G. de Rooij,

Affiliation Center for Reproductive Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Maria Jasin,

Affiliation Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
⨯
P. Jeremy Wang

* E-mail: pwang@vet.upenn.edu

Affiliation Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis

Mengcheng Luo,
Jian Zhou,
N. Adrian Leu,
Carla M. Abreu,
Jianle Wang,
Montserrat C. Anguera,
Dirk G. de Rooij,
Maria Jasin,
P. Jeremy Wang

Published: January 29, 2015
https://doi.org/10.1371/journal.pgen.1004954

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