Interactions of Chromatin Context, Binding Site Sequence Content, and Sequence Evolution in Stress-Induced p53 Occupancy and Transactivation

Dan Su; Xuting Wang; Michelle R. Campbell; Lingyun Song; Alexias Safi; Gregory E. Crawford; Douglas A. Bell

doi:10.1371/journal.pgen.1004885

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Open Access

Peer-reviewed

Research Article

Interactions of Chromatin Context, Binding Site Sequence Content, and Sequence Evolution in Stress-Induced p53 Occupancy and Transactivation

Dan Su ,

Contributed equally to this work with: Dan Su, Xuting Wang

Affiliation Environmental Genomics Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Xuting Wang ,

Contributed equally to this work with: Dan Su, Xuting Wang

Affiliation Environmental Genomics Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Michelle R. Campbell,

Affiliation Environmental Genomics Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Lingyun Song,

Affiliation Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America
⨯
Alexias Safi,

Affiliation Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America
⨯
Gregory E. Crawford,

Affiliation Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America
⨯
Douglas A. Bell

* E-mail: BELL1@niehs.nih.gov

Affiliation Environmental Genomics Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯

Interactions of Chromatin Context, Binding Site Sequence Content, and Sequence Evolution in Stress-Induced p53 Occupancy and Transactivation

Dan Su,
Xuting Wang,
Michelle R. Campbell,
Lingyun Song,
Alexias Safi,
Gregory E. Crawford,
Douglas A. Bell

Published: January 8, 2015
https://doi.org/10.1371/journal.pgen.1004885

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Chromatin
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Gene expression
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Transposable elements
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Sequence motif analysis
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Bone density
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Transactivation
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Cell binding
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Mammalian genomics
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