Increased and Imbalanced dNTP Pools Symmetrically Promote Both Leading and Lagging Strand Replication Infidelity

• Robert J. Buckland,

  Affiliations Department of Medical Biochemistry and Biophysics, Umea University, Umea, Sweden, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umea University, Umea, Sweden

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• Danielle L. Watt,

  Affiliation Laboratory of Molecular Genetics and Laboratory of Structural Biology, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina, United States of America

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• Balasubramanyam Chittoor,

  Affiliation Department of Medical Biochemistry and Biophysics, Umea University, Umea, Sweden

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• Anna Karin Nilsson,

  Affiliation Department of Medical Biochemistry and Biophysics, Umea University, Umea, Sweden

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• Thomas A. Kunkel,

  Affiliation Laboratory of Molecular Genetics and Laboratory of Structural Biology, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina, United States of America

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• Andrei Chabes

  * E-mail: andrei.chabes@medchem.umu.se

  Affiliations Department of Medical Biochemistry and Biophysics, Umea University, Umea, Sweden, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umea University, Umea, Sweden

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