Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans

Ramesh Ratnappan; Francis R. G. Amrit; Shaw-Wen Chen; Hasreet Gill; Kyle Holden; Jordan Ward; Keith R. Yamamoto; Carissa P. Olsen; Arjumand Ghazi

doi:10.1371/journal.pgen.1004829

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Research Article

Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans

Ramesh Ratnappan,

Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Francis R. G. Amrit,

Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Shaw-Wen Chen,

Affiliation Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Hasreet Gill,

Current address: Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Kyle Holden,

Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Jordan Ward,

Affiliation Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California, United States of America
⨯
Keith R. Yamamoto,

Affiliation Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California, United States of America
⨯
Carissa P. Olsen,

Affiliation Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Arjumand Ghazi

* E-mail: arjumand.ghazi@chp.edu

Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯

Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans

Ramesh Ratnappan,
Francis R. G. Amrit,
Shaw-Wen Chen,
Hasreet Gill,
Kyle Holden,
Jordan Ward,
Keith R. Yamamoto,
Carissa P. Olsen,
Arjumand Ghazi

Published: December 4, 2014
https://doi.org/10.1371/journal.pgen.1004829

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