Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant

• Anja Wartenberg,

  Affiliation Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knoell Institute Jena (HKI), Jena, Germany

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• Jörg Linde,

  Affiliation Research Group Systems Biology & Bioinformatics, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knoell Institute Jena (HKI), Jena, Germany

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• Ronny Martin,

  Affiliation Septomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology –Hans Knoell Institute, Jena, Germany

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• Maria Schreiner,

  Affiliation Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knoell Institute Jena (HKI), Jena, Germany

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• Fabian Horn,

  Affiliation Research Group Systems Biology & Bioinformatics, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knoell Institute Jena (HKI), Jena, Germany

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• Ilse D. Jacobsen,

  Affiliations Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knoell Institute Jena (HKI), Jena, Germany, Research Group Microbial Immunology, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knoell Institute Jena (HKI), Jena, Germany

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• Sabrina Jenull,

  Affiliation Medical University Vienna, Max F. Perutz Laboratories, Department of Medical Biochemistry, Vienna, Austria

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• Thomas Wolf,

  Affiliation Research Group Systems Biology & Bioinformatics, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knoell Institute Jena (HKI), Jena, Germany

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• Karl Kuchler,

  Affiliation Medical University Vienna, Max F. Perutz Laboratories, Department of Medical Biochemistry, Vienna, Austria

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• Reinhard Guthke,

  Affiliation Research Group Systems Biology & Bioinformatics, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knoell Institute Jena (HKI), Jena, Germany

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• Oliver Kurzai,

  Affiliation Septomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology –Hans Knoell Institute, Jena, Germany

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• Anja Forche,

  Affiliation Department of Biology, Bowdoin College, Brunswick, Maine, United States of America

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• Christophe d'Enfert,

  Affiliations Institut Pasteur, Unité Biologie et Pathogénicité Fongiques, Département Génomes et Génétique, Paris, France, INRA, USC2019, Paris, France

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• Sascha Brunke ,

  Contributed equally to this work with: Sascha Brunke, Bernhard Hube

  Affiliations Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knoell Institute Jena (HKI), Jena, Germany, Integrated Research and Treatment Center, Sepsis und Sepsisfolgen, Center for Sepsis Control and Care (CSCC), Universitätsklinikum Jena, Germany

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• Bernhard Hube

  Contributed equally to this work with: Sascha Brunke, Bernhard Hube

  * E-mail: bernhard.hube@hki-jena.de

  Affiliations Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knoell Institute Jena (HKI), Jena, Germany, Integrated Research and Treatment Center, Sepsis und Sepsisfolgen, Center for Sepsis Control and Care (CSCC), Universitätsklinikum Jena, Germany, Friedrich Schiller University, Jena, Germany

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