The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy

Joe H. Pogson; Rachael M. Ivatt; Alvaro Sanchez-Martinez; Roberta Tufi; Emma Wilson; Heather Mortiboys; Alexander J. Whitworth

doi:10.1371/journal.pgen.1004815

Loading metrics

Open Access

Peer-reviewed

Research Article

The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy

Joe H. Pogson,

Affiliations MRC Centre for Developmental and Biomedical Genetics, Sheffield, United Kingdom, Department of Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯
Rachael M. Ivatt ,

Contributed equally to this work with: Rachael M. Ivatt, Alvaro Sanchez-Martinez, Roberta Tufi

Affiliations MRC Centre for Developmental and Biomedical Genetics, Sheffield, United Kingdom, Department of Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯
Alvaro Sanchez-Martinez ,

Contributed equally to this work with: Rachael M. Ivatt, Alvaro Sanchez-Martinez, Roberta Tufi

Affiliations MRC Centre for Developmental and Biomedical Genetics, Sheffield, United Kingdom, Department of Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯
Roberta Tufi ,

Contributed equally to this work with: Rachael M. Ivatt, Alvaro Sanchez-Martinez, Roberta Tufi

Affiliations MRC Centre for Developmental and Biomedical Genetics, Sheffield, United Kingdom, Department of Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯
Emma Wilson,

Affiliations MRC Centre for Developmental and Biomedical Genetics, Sheffield, United Kingdom, Department of Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯
Heather Mortiboys,

Affiliation Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, United Kingdom
⨯
Alexander J. Whitworth

* E-mail: a.whitworth@sheffield.ac.uk

Affiliations MRC Centre for Developmental and Biomedical Genetics, Sheffield, United Kingdom, Department of Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯

The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy

Joe H. Pogson,
Rachael M. Ivatt,
Alvaro Sanchez-Martinez,
Roberta Tufi,
Emma Wilson,
Heather Mortiboys,
Alexander J. Whitworth

Published: November 20, 2014
https://doi.org/10.1371/journal.pgen.1004815

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mitochondria
Is the Subject Area "Mitochondria" applicable to this article?

Thanks for your feedback.
Drosophila melanogaster
Is the Subject Area "Drosophila melanogaster" applicable to this article?

Thanks for your feedback.
RNA interference
Is the Subject Area "RNA interference" applicable to this article?

Thanks for your feedback.
Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
Phenotypes
Is the Subject Area "Phenotypes" applicable to this article?

Thanks for your feedback.
Phosphatases
Is the Subject Area "Phosphatases" applicable to this article?

Thanks for your feedback.
Hyperexpression techniques
Is the Subject Area "Hyperexpression techniques" applicable to this article?

Thanks for your feedback.
Protein kinases
Is the Subject Area "Protein kinases" applicable to this article?

Thanks for your feedback.