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Open Access
Peer-reviewed
Research Article
The Tau Tubulin Kinases TTBK1/2 Promote Accumulation of Pathological TDP-43
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Nicole F. Liachko,
Affiliations Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America
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Pamela J. McMillan ,
Contributed equally to this work with: Pamela J. McMillan, Timothy J. Strovas
Affiliations Mental Illness Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, United States of America
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Timothy J. Strovas ,
Contributed equally to this work with: Pamela J. McMillan, Timothy J. Strovas
Affiliation Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America
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Elaine Loomis,
Affiliation Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America
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Lynne Greenup,
Affiliation Mental Illness Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America
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Jill R. Murrell,
Affiliation Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Bernardino Ghetti,
Affiliation Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Murray A. Raskind,
Affiliations Department of Medicine, University of Washington, Seattle, Washington, United States of America, Mental Illness Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America
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Thomas J. Montine,
Affiliations Department of Neurology, University of Washington, Seattle, Washington, United States of America, Parkinson's Disease Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America, Department of Pathology, University of Washington, Seattle, Washington, United States of America
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Thomas D. Bird,
Affiliations Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America, Department of Neurology, University of Washington, Seattle, Washington, United States of America
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James B. Leverenz,
Affiliations Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America, Mental Illness Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, United States of America, Department of Neurology, University of Washington, Seattle, Washington, United States of America, Parkinson's Disease Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America
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Brian C. Kraemer
* E-mail: kraemerb@u.washington.edu
Affiliations Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, United States of America
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The Tau Tubulin Kinases TTBK1/2 Promote Accumulation of Pathological TDP-43
- Nicole F. Liachko,
- Pamela J. McMillan,
- Timothy J. Strovas,
- Elaine Loomis,
- Lynne Greenup,
- Jill R. Murrell,
- Bernardino Ghetti,
- Murray A. Raskind,
- Thomas J. Montine,
- Thomas D. Bird
- Published: December 4, 2014
- https://doi.org/10.1371/journal.pgen.1004803