MMS Exposure Promotes Increased MtDNA Mutagenesis in the Presence of Replication-Defective Disease-Associated DNA Polymerase γ Variants

Open Access

Peer-reviewed

Research Article

Jeffrey D. Stumpf,

Affiliation Mitochondrial DNA Replication Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina, United States of America
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William C. Copeland

* E-mail: copelan1@niehs.nih.gov

Affiliation Mitochondrial DNA Replication Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina, United States of America
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Mitochondrial DNA
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Mutagenesis
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Polymerases
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DNA replication
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Mitochondria
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Point mutation
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Mutation
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Heterozygosity
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