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Open Access
Peer-reviewed
Research Article
Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation
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Diana F. Lázaro,
Affiliation Department of NeuroDegeneration and Restorative Research, Center for Nanoscale Microscopy and Molecular Physiology of the Brain University Medical Goettingen, Goettingen, Germany
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Eva F. Rodrigues,
Affiliation Department of NeuroDegeneration and Restorative Research, Center for Nanoscale Microscopy and Molecular Physiology of the Brain University Medical Goettingen, Goettingen, Germany
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Ramona Langohr,
Affiliation Department of Neurology, Ulm University, Ulm, Germany
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Hedieh Shahpasandzadeh,
Affiliation Georg August University, Institute for Microbiology and Genetics Dept. of Molecular Microbiology and Genetics, Goettingen, Germany
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Thales Ribeiro,
Affiliation Laboratório de Citotoxicidade e Genotoxicidade, Departamento de Bioquímica - Instituto de Química Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Patrícia Guerreiro,
Affiliations Department of NeuroDegeneration and Restorative Research, Center for Nanoscale Microscopy and Molecular Physiology of the Brain University Medical Goettingen, Goettingen, Germany, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal
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Ellen Gerhardt,
Affiliation Department of NeuroDegeneration and Restorative Research, Center for Nanoscale Microscopy and Molecular Physiology of the Brain University Medical Goettingen, Goettingen, Germany
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Katharina Kröhnert,
Affiliation Department of Neuro and Sensory Physiology, University of Göttingen Medical Center c/o European Neuroscience Institute Göttingen, Göttingen, Germany
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Jochen Klucken,
Affiliation Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangan, Germany
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Marcos D. Pereira,
Affiliation Laboratório de Citotoxicidade e Genotoxicidade, Departamento de Bioquímica - Instituto de Química Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Blagovesta Popova,
Affiliation Georg August University, Institute for Microbiology and Genetics Dept. of Molecular Microbiology and Genetics, Goettingen, Germany
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Niels Kruse,
Affiliation Institute for Neuropathology, University Medical Center Goettingen, Goettingen, Germany
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Brit Mollenhauer,
Affiliations Institute for Neuropathology, University Medical Center Goettingen, Goettingen, Germany, The Department for neurosurgery at UMG and Paracelsus-Elena-Klinik, Kassel, Germany
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Silvio O. Rizzoli,
Affiliation Department of Neuro and Sensory Physiology, University of Göttingen Medical Center c/o European Neuroscience Institute Göttingen, Göttingen, Germany
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Gerhard H. Braus,
Affiliation Georg August University, Institute for Microbiology and Genetics Dept. of Molecular Microbiology and Genetics, Goettingen, Germany
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Karin M. Danzer,
Affiliation Department of Neurology, Ulm University, Ulm, Germany
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Tiago F. Outeiro
* E-mail: touteir@gwdg.de
Affiliations Department of NeuroDegeneration and Restorative Research, Center for Nanoscale Microscopy and Molecular Physiology of the Brain University Medical Goettingen, Goettingen, Germany, Laboratório de Citotoxicidade e Genotoxicidade, Departamento de Bioquímica - Instituto de Química Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation
- Diana F. Lázaro,
- Eva F. Rodrigues,
- Ramona Langohr,
- Hedieh Shahpasandzadeh,
- Thales Ribeiro,
- Patrícia Guerreiro,
- Ellen Gerhardt,
- Katharina Kröhnert,
- Jochen Klucken,
- Marcos D. Pereira
- Published: November 13, 2014
- https://doi.org/10.1371/journal.pgen.1004741