BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin

Xiao-Jing Zhu; YuDong Liu; Zhong-Min Dai; Xiaoyun Zhang; XueQin Yang; Yan Li; Mengsheng Qiu; Jiang Fu; Wei Hsu; YiPing Chen; Zunyi Zhang

doi:10.1371/journal.pgen.1004687

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Open Access

Peer-reviewed

Research Article

BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin

Xiao-Jing Zhu,

Affiliations Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University, Zhejiang, China, Key Laboratory of Mammalian Organogenesis and Regeneration, Zhejiang, China
⨯
YuDong Liu,

Affiliations Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University, Zhejiang, China, Key Laboratory of Mammalian Organogenesis and Regeneration, Zhejiang, China
⨯
Zhong-Min Dai,

Affiliations Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University, Zhejiang, China, Key Laboratory of Mammalian Organogenesis and Regeneration, Zhejiang, China
⨯
Xiaoyun Zhang,

Affiliations Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University, Zhejiang, China, Key Laboratory of Mammalian Organogenesis and Regeneration, Zhejiang, China
⨯
XueQin Yang,

Affiliations Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University, Zhejiang, China, Key Laboratory of Mammalian Organogenesis and Regeneration, Zhejiang, China
⨯
Yan Li,

Affiliations Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University, Zhejiang, China, Key Laboratory of Mammalian Organogenesis and Regeneration, Zhejiang, China
⨯
Mengsheng Qiu,

Affiliations Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University, Zhejiang, China, Key Laboratory of Mammalian Organogenesis and Regeneration, Zhejiang, China
⨯
Jiang Fu,

Affiliation Department of Biomedical Genetics, Center for Oral Biology, James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, New York, United States of America
⨯
Wei Hsu,

Affiliation Department of Biomedical Genetics, Center for Oral Biology, James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, New York, United States of America
⨯
YiPing Chen,

Affiliation Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana, United States of America
⨯
Zunyi Zhang

* E-mail: zunyi_zhang@idrbio.org

Affiliations Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University, Zhejiang, China, Key Laboratory of Mammalian Organogenesis and Regeneration, Zhejiang, China
⨯

BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin

Xiao-Jing Zhu,
YuDong Liu,
Zhong-Min Dai,
Xiaoyun Zhang,
XueQin Yang,
Yan Li,
Mengsheng Qiu,
Jiang Fu,
Wei Hsu,
YiPing Chen

Published: October 16, 2014
https://doi.org/10.1371/journal.pgen.1004687

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Epidermis
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BMP signaling
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Dermis
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Wnt signaling cascade
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Basal cells
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Genetically modified animals
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Keratinocytes
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Developmental signaling
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