Selection on a Variant Associated with Improved Viral Clearance Drives Local, Adaptive Pseudogenization of Interferon Lambda 4 (IFNL4)

• Felix M. Key,

  Affiliation Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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• Benjamin Peter,

  Affiliation Department of Integrative Biology, University of California Berkeley, Berkeley, California, United States of America

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• Megan Y. Dennis,

  Affiliation Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington, United States of America

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• Emilia Huerta-Sánchez,

  Affiliation School of Natural Sciences, University of California Merced, Merced, California, United States of America

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• Wei Tang,

  Affiliation Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Ludmila Prokunina-Olsson,

  Affiliation Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Rasmus Nielsen,

  Affiliation Department of Integrative Biology, University of California Berkeley, Berkeley, California, United States of America

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• Aida M. Andrés

  * E-mail: aida_andres@eva.mpg.de

  Affiliation Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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