SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene

Xin-Hua Cheng; Markaisa Black; Vladimir Ustiyan; Tien Le; Logan Fulford; Anusha Sridharan; Mario Medvedovic; Vladimir V. Kalinichenko; Jeffrey A. Whitsett; Tanya V. Kalin

doi:10.1371/journal.pgen.1004656

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Open Access

Peer-reviewed

Research Article

SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene

Xin-Hua Cheng ,

Contributed equally to this work with: Xin-Hua Cheng, Markaisa Black

Affiliation Division of Pulmonary Biology, the Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, Ohio, United States of America
⨯
Markaisa Black ,

Contributed equally to this work with: Xin-Hua Cheng, Markaisa Black

Affiliation Division of Pulmonary Biology, the Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, Ohio, United States of America
⨯
Vladimir Ustiyan,

Affiliation Division of Pulmonary Biology, the Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, Ohio, United States of America
⨯
Tien Le,

Affiliation Division of Pulmonary Biology, the Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, Ohio, United States of America
⨯
Logan Fulford,

Affiliation Division of Pulmonary Biology, the Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, Ohio, United States of America
⨯
Anusha Sridharan,

Affiliation Division of Pulmonary Biology, the Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, Ohio, United States of America
⨯
Mario Medvedovic,

Affiliation Department of Environmental Health, College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America
⨯
Vladimir V. Kalinichenko,

Affiliation Division of Pulmonary Biology, the Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, Ohio, United States of America
⨯
Jeffrey A. Whitsett,

Affiliation Division of Pulmonary Biology, the Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, Ohio, United States of America
⨯
Tanya V. Kalin

* E-mail: Tatiana.kalin@cchmc.org

Affiliation Division of Pulmonary Biology, the Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, Ohio, United States of America
⨯

SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene

Xin-Hua Cheng,
Markaisa Black,
Vladimir Ustiyan,
Tien Le,
Logan Fulford,
Anusha Sridharan,
Mario Medvedovic,
Vladimir V. Kalinichenko,
Jeffrey A. Whitsett,
Tanya V. Kalin

Published: September 25, 2014
https://doi.org/10.1371/journal.pgen.1004656

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