Muscular Dystrophy-Associated SUN1 and SUN2 Variants Disrupt Nuclear-Cytoskeletal Connections and Myonuclear Organization

• Peter Meinke ,

  Contributed equally to this work with: Peter Meinke, Elisabetta Mattioli, Farhana Haque

  Current address: The Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

  Affiliation Institute of Human Genetics and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany

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• Elisabetta Mattioli ,

  Contributed equally to this work with: Peter Meinke, Elisabetta Mattioli, Farhana Haque

  Affiliations National Research Council of Italy - CNR - Institute for Molecular Genetics, Unit of Bologna IOR, Bologna, Italy, Rizzoli Orthopaedic Institute, Laboratory of Musculoskeletal Cell Biology, Bologna, Italy

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• Farhana Haque ,

  Contributed equally to this work with: Peter Meinke, Elisabetta Mattioli, Farhana Haque

  Affiliation Department of Biochemistry, University of Leicester, Leicester, United Kingdom

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• Susumu Antoku,

  Affiliation Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

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• Marta Columbaro,

  Affiliation Rizzoli Orthopaedic Institute, Laboratory of Musculoskeletal Cell Biology, Bologna, Italy

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• Kees R. Straatman,

  Affiliation Centre for Core Biotechnology Services, University of Leicester, Leicester, United Kingdom

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• Howard J. Worman,

  Affiliations Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

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• Gregg G. Gundersen,

  Affiliation Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

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• Giovanna Lattanzi,

  Affiliations National Research Council of Italy - CNR - Institute for Molecular Genetics, Unit of Bologna IOR, Bologna, Italy, Rizzoli Orthopaedic Institute, Laboratory of Musculoskeletal Cell Biology, Bologna, Italy

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• Manfred Wehnert,

  Current address: Retired, Rostock, Germany

  Affiliation Institute of Human Genetics and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany

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• Sue Shackleton

  * E-mail: ss115@le.ac.uk

  Affiliation Department of Biochemistry, University of Leicester, Leicester, United Kingdom

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