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Open Access
Peer-reviewed
Research Article
A Gain-of-Function Mutation in Tnni2 Impeded Bone Development through Increasing Hif3a Expression in DA2B Mice
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Xiaoquan Zhu ,
Contributed equally to this work with: Xiaoquan Zhu, Fengchao Wang
Affiliations Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing, China, National Institute of Biological Sciences (NIBS), Beijing, China
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Fengchao Wang ,
Contributed equally to this work with: Xiaoquan Zhu, Fengchao Wang
Affiliation National Institute of Biological Sciences (NIBS), Beijing, China
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Yanyang Zhao,
Affiliation Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing, China
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Peng Yang,
Affiliation National Institute of Biological Sciences (NIBS), Beijing, China
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Jun Chen,
Affiliation National Institute of Biological Sciences (NIBS), Beijing, China
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Hanzi Sun,
Affiliation National Institute of Biological Sciences (NIBS), Beijing, China
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Lei Liu,
Affiliation National Institute of Biological Sciences (NIBS), Beijing, China
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Wenjun Li,
Affiliation National Institute of Biological Sciences (NIBS), Beijing, China
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Lin Pan,
Affiliation Clinical Institute of China-Japan Friendship Hospital, Beijing, China
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Yanru Guo,
Affiliation Clinical Institute of China-Japan Friendship Hospital, Beijing, China
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Zhaohui Kou,
Affiliation National Institute of Biological Sciences (NIBS), Beijing, China
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Yu Zhang,
Affiliation National Institute of Biological Sciences (NIBS), Beijing, China
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Cheng Zhou,
Affiliation Department of Radiology, Beijing Hospital, Ministry of Health, Beijing, China
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Jiang He,
Affiliation Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, United States of America
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Xue Zhang,
Affiliation Center for Genetic Medicine and State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
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Jianxin Li,
Affiliation The Key Laboratory of Reproductive Health, Liaoning, China
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Weitian Han,
Affiliation The Key Laboratory of Reproductive Health, Liaoning, China
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Jian Li,
Affiliation Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing, China
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Guanghui Liu,
Affiliation National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
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Shaorong Gao ,
* E-mail: gaoshaorong@tongji.edu.cn (SG); yangze.nig@gmail.com (ZY)
Affiliations National Institute of Biological Sciences (NIBS), Beijing, China, School of Life Sciences and Technology, Tongji University, Shanghai, China
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Ze Yang
* E-mail: gaoshaorong@tongji.edu.cn (SG); yangze.nig@gmail.com (ZY)
Affiliation Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing, China
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A Gain-of-Function Mutation in Tnni2 Impeded Bone Development through Increasing Hif3a Expression in DA2B Mice
- Xiaoquan Zhu,
- Fengchao Wang,
- Yanyang Zhao,
- Peng Yang,
- Jun Chen,
- Hanzi Sun,
- Lei Liu,
- Wenjun Li,
- Lin Pan,
- Yanru Guo
- Published: October 23, 2014
- https://doi.org/10.1371/journal.pgen.1004589