Positive Selection and Multiple Losses of the LINE-1-Derived L1TD1 Gene in Mammals Suggest a Dual Role in Genome Defense and Pluripotency

• Richard N. McLaughlin Jr. ,

  Contributed equally to this work with: Richard N. McLaughlin Jr., Janet M. Young

  Affiliation Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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• Janet M. Young ,

  Contributed equally to this work with: Richard N. McLaughlin Jr., Janet M. Young

  Affiliation Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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• Lei Yang,

  Current address: Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  Affiliation Department of Biological Sciences & Institute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, Idaho, United States of America

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• Rafik Neme,

  Affiliation Max-Planck Institute for Evolutionary Biology, Plön, Germany

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• Holly A. Wichman,

  Affiliation Department of Biological Sciences & Institute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, Idaho, United States of America

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• Harmit S. Malik

  * E-mail: hsmalik@fhcrc.org

  Affiliations Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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