Conditional Inactivation of Upstream Binding Factor Reveals Its Epigenetic Functions and the Existence of a Somatic Nucleolar Precursor Body

Nourdine Hamdane; Victor Y. Stefanovsky; Michel G. Tremblay; Attila Németh; Eric Paquet; Frédéric Lessard; Elaine Sanij; Ross Hannan; Tom Moss

doi:10.1371/journal.pgen.1004505

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Open Access

Peer-reviewed

Research Article

Conditional Inactivation of Upstream Binding Factor Reveals Its Epigenetic Functions and the Existence of a Somatic Nucleolar Precursor Body

Nourdine Hamdane,

Affiliations Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada, Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Québec, Canada
⨯
Victor Y. Stefanovsky,

Affiliations Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada, Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Québec, Canada
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Michel G. Tremblay,

Affiliations Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada, Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Québec, Canada
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Attila Németh,

Affiliation Department of Biochemistry III, Biochemistry Center Regensburg, University of Regensburg, Regensburg, Germany
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Eric Paquet,

Affiliation Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada
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Frédéric Lessard,

Current address: Department of Biochemistry, Pavillon Roger-Gaudry, University of Montreal, Montréal, Canada

Affiliations Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada, Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Québec, Canada
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Elaine Sanij,

Affiliations Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia, Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
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Ross Hannan,

Affiliations Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia, Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
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Tom Moss

* E-mail: Tom.Moss@crhdq.ulaval.ca

Affiliations Laboratory of Growth and Development, St-Patrick Research Group in Basic Oncology, Cancer Division of the Quebec University Hospital Research Centre, Edifice St Patrick, Québec, Québec, Canada, Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Québec, Québec, Canada
⨯

Conditional Inactivation of Upstream Binding Factor Reveals Its Epigenetic Functions and the Existence of a Somatic Nucleolar Precursor Body

Nourdine Hamdane,
Victor Y. Stefanovsky,
Michel G. Tremblay,
Attila Németh,
Eric Paquet,
Frédéric Lessard,
Elaine Sanij,
Ross Hannan,
Tom Moss

Published: August 14, 2014
https://doi.org/10.1371/journal.pgen.1004505

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DNA methylation
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