Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment

• John P. Kemp ,

  Contributed equally to this work with: John P. Kemp, Carolina Medina-Gomez

  * E-mail: j.p.kemp@bristol.ac.uk

  Affiliations MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom, University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia

  ⨯
• Carolina Medina-Gomez ,

  Contributed equally to this work with: John P. Kemp, Carolina Medina-Gomez

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands

  ⨯
• Karol Estrada,

  Affiliation Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
• Beate St Pourcain,

  Affiliations MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom, School of Oral and Dental Sciences, University of Bristol, Bristol, United Kingdom, School of Experimental Psychology, University of Bristol, Bristol, United Kingdom

  ⨯
• Denise H. M. Heppe,

  Affiliations The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Paediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Nicole M. Warrington,

  Affiliation University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia

  ⨯
• Ling Oei,

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands

  ⨯
• Susan M. Ring,

  Affiliation MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom

  ⨯
• Claudia J. Kruithof,

  Affiliations The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Nicholas J. Timpson,

  Affiliation MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom

  ⨯
• Lisa E. Wolber,

  Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

  ⨯
• Sjur Reppe,

  Affiliation Department of Medical Biochemistry, Oslo University Hospital, Ullevaal, Oslo, Norway

  ⨯
• Kaare Gautvik,

  Affiliations Department of Medical Biochemistry, Oslo University Hospital, Ullevaal, Oslo, Norway, Department of Medical Biochemistry, Oslo Deacon Hospital, Oslo, Norway

  ⨯
• Elin Grundberg,

  Affiliations Department of Human Genetics, McGill University, Montréal, Canada, McGill University and Genome Québec Innovation Centre, Montréal, Canada

  ⨯
• Bing Ge,

  Affiliation McGill University and Genome Québec Innovation Centre, Montréal, Canada

  ⨯
• Bram van der Eerden,

  Affiliation Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Jeroen van de Peppel,

  Affiliation Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Matthew A. Hibbs,

  Affiliations Department of Computer Science, Trinity University, San Antonio, Texas, United States of America, The Jackson Laboratory, Bar Harbor, Maine, United States of America

  ⨯
• Cheryl L. Ackert-Bicknell,

  Affiliation The Jackson Laboratory, Bar Harbor, Maine, United States of America

  ⨯
• Kwangbom Choi,

  Affiliation The Jackson Laboratory, Bar Harbor, Maine, United States of America

  ⨯
• Daniel L. Koller,

  Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

  ⨯
• Michael J. Econs,

  Affiliations Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

  ⨯
• Frances M. K. Williams,

  Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

  ⨯
• Tatiana Foroud,

  Affiliation Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

  ⨯
• M. Carola Zillikens,

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands

  ⨯
• Claes Ohlsson,

  Affiliation Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

  ⨯
• Albert Hofman,

  Affiliations The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands

  ⨯
• André G. Uitterlinden,

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands

  ⨯
• George Davey Smith,

  Affiliation MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom

  ⨯
• Vincent W. V. Jaddoe,

  Affiliations The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Paediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Jonathan H. Tobias ,

  ¶JHT, FR and DME are joint senior authors on this work.

  Affiliation School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

  ⨯
• Fernando Rivadeneira ,

  ¶JHT, FR and DME are joint senior authors on this work.

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands

  ⨯
•  [ ... ],
• David M. Evans

  ¶JHT, FR and DME are joint senior authors on this work.

  Affiliations MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom, University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia

  ⨯
• [ view all ]
• [ view less ]