ATRA-Induced Cellular Differentiation and CD38 Expression Inhibits Acquisition of BCR-ABL Mutations for CML Acquired Resistance

Zhiqiang Wang; Zheng Liu; Xiwei Wu; Su Chu; Jinhui Wang; Hongfeng Yuan; Mendel Roth; Yate-Ching Yuan; Ravi Bhatia; WenYong Chen

doi:10.1371/journal.pgen.1004414

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Open Access

Peer-reviewed

Research Article

ATRA-Induced Cellular Differentiation and CD38 Expression Inhibits Acquisition of BCR-ABL Mutations for CML Acquired Resistance

Zhiqiang Wang ,

Contributed equally to this work with: Zhiqiang Wang, Zheng Liu

Affiliation Department of Cancer Biology, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Zheng Liu ,

Contributed equally to this work with: Zhiqiang Wang, Zheng Liu

Affiliation Department of Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Xiwei Wu,

Affiliation Department of Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Su Chu,

Affiliation Division of Hematopoietic Stem Cell and Leukemia Research, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Jinhui Wang,

Affiliation Department of Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Hongfeng Yuan,

Affiliation Department of Cancer Biology, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Mendel Roth,

Affiliation Department of Cancer Biology, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Yate-Ching Yuan,

Affiliation Department of Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
Ravi Bhatia,

Affiliation Division of Hematopoietic Stem Cell and Leukemia Research, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯
WenYong Chen

* E-mail: wechen@coh.org

Affiliation Department of Cancer Biology, Beckman Research Institute, City of Hope, Duarte, California, United States of America
⨯

ATRA-Induced Cellular Differentiation and CD38 Expression Inhibits Acquisition of BCR-ABL Mutations for CML Acquired Resistance

Zhiqiang Wang,
Zheng Liu,
Xiwei Wu,
Su Chu,
Jinhui Wang,
Hongfeng Yuan,
Mendel Roth,
Yate-Ching Yuan,
Ravi Bhatia,
WenYong Chen

Published: June 26, 2014
https://doi.org/10.1371/journal.pgen.1004414

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