Rapid Evolution of PARP Genes Suggests a Broad Role for ADP-Ribosylation in Host-Virus Conflicts

Open Access

Peer-reviewed

Research Article

Matthew D. Daugherty,

Affiliation Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Janet M. Young,

Affiliation Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Julie A. Kerns,

Affiliations Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Institute for Systems Biology, Seattle, Washington, United States of America
⨯
Harmit S. Malik

* E-mail: hsmalik@fhcrc.org

Affiliations Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Evolutionary genetics
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Primates
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Viral evolution
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Evolutionary immunology
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ADP-ribosylation
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Mammalian genomics
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Sequence alignment
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Protein domains
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