An Epigenetic Signature in Peripheral Blood Associated with the Haplotype on 17q21.31, a Risk Factor for Neurodegenerative Tauopathy

• Yun Li ,

  Contributed equally to this work with: Yun Li, Jason A. Chen

  Affiliation Department of Psychiatry and Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Jason A. Chen ,

  Contributed equally to this work with: Yun Li, Jason A. Chen

  Affiliation Interdepartmental Program in Bioinformatics, University of California Los Angeles, Los Angeles, California, United States of America

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• Renee L. Sears,

  Affiliation Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Fuying Gao,

  Affiliation Department of Psychiatry and Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Eric D. Klein,

  Affiliation Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Anna Karydas,

  Affiliation Memory and Aging Center/Sandler Neurosciences Center, University of California San Francisco, San Francisco, California, United States of America

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• Michael D. Geschwind,

  Affiliation Memory and Aging Center/Sandler Neurosciences Center, University of California San Francisco, San Francisco, California, United States of America

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• Howard J. Rosen,

  Affiliation Memory and Aging Center/Sandler Neurosciences Center, University of California San Francisco, San Francisco, California, United States of America

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• Adam L. Boxer,

  Affiliation Memory and Aging Center/Sandler Neurosciences Center, University of California San Francisco, San Francisco, California, United States of America

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• Weilong Guo,

  Affiliations Bioinformatics Division and Center for Synthetic & Systems Biology, TNLIST, Tsinghua University, Beijing, China, Department of Molecular, Cell and Developmental Biology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Matteo Pellegrini,

  Affiliation Department of Molecular, Cell and Developmental Biology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Steve Horvath,

  Affiliation Departments of Biostatistics and Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Bruce L. Miller,

  Affiliation Memory and Aging Center/Sandler Neurosciences Center, University of California San Francisco, San Francisco, California, United States of America

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• Daniel H. Geschwind,

  Affiliations Department of Psychiatry and Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Giovanni Coppola

  * E-mail: gcoppola@ucla.edu

  Affiliations Department of Psychiatry and Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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