An Evolutionary Analysis of Antigen Processing and Presentation across Different Timescales Reveals Pervasive Selection

• Diego Forni ,

  Contributed equally to this work with: Diego Forni, Rachele Cagliani

  Affiliation Scientific Institute IRCCS E. MEDEA, Bioinformatics, Bosisio Parini, Italy

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• Rachele Cagliani ,

  Contributed equally to this work with: Diego Forni, Rachele Cagliani

  Affiliation Scientific Institute IRCCS E. MEDEA, Bioinformatics, Bosisio Parini, Italy

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• Claudia Tresoldi,

  Affiliation Scientific Institute IRCCS E. MEDEA, Bioinformatics, Bosisio Parini, Italy

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• Uberto Pozzoli,

  Affiliation Scientific Institute IRCCS E. MEDEA, Bioinformatics, Bosisio Parini, Italy

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• Luca De Gioia,

  Affiliation Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy

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• Giulia Filippi,

  Affiliation Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, Italy

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• Stefania Riva,

  Affiliation Scientific Institute IRCCS E. MEDEA, Bioinformatics, Bosisio Parini, Italy

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• Giorgia Menozzi,

  Affiliation Scientific Institute IRCCS E. MEDEA, Bioinformatics, Bosisio Parini, Italy

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• Marta Colleoni,

  Affiliation Scientific Institute IRCCS E. MEDEA, Bioinformatics, Bosisio Parini, Italy

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• Mara Biasin,

  Affiliation Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy

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• Sergio Lo Caputo,

  Affiliation Infectious Disease Unit, S. Maria Annunziata Hospital, Florence, Italy

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• Francesco Mazzotta,

  Affiliation Infectious Disease Unit, S. Maria Annunziata Hospital, Florence, Italy

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• Giacomo P. Comi,

  Affiliation Dino Ferrari Centre, Department of Physiopathology and Transplantation, University of Milan, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico, Milan, Italy

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• Nereo Bresolin,

  Affiliations Scientific Institute IRCCS E. MEDEA, Bioinformatics, Bosisio Parini, Italy, Dino Ferrari Centre, Department of Physiopathology and Transplantation, University of Milan, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico, Milan, Italy

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• Mario Clerici,

  Affiliations Chair of Immunology, Department of Physiopathology and Transplantation, University of Milan, Milan, Italy, Don C. Gnocchi Foundation ONLUS, IRCCS, Milan, Italy

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•  [ ... ],
• Manuela Sironi

  * E-mail: manuela.sironi@bp.lnf.it

  Affiliation Scientific Institute IRCCS E. MEDEA, Bioinformatics, Bosisio Parini, Italy

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