Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli

• Mohan Babu ,

  Contributed equally to this work with: Mohan Babu, Roland Arnold, Cedoljub Bundalovic-Torma, Alla Gagarinova, Keith S. Wong

  * E-mail: mohan.babu@uregina.ca (MB); andrew.emili@utoronto.ca (AE)

  Affiliations Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada

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• Roland Arnold ,

  Contributed equally to this work with: Mohan Babu, Roland Arnold, Cedoljub Bundalovic-Torma, Alla Gagarinova, Keith S. Wong

  Affiliation Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada

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• Cedoljub Bundalovic-Torma ,

  Contributed equally to this work with: Mohan Babu, Roland Arnold, Cedoljub Bundalovic-Torma, Alla Gagarinova, Keith S. Wong

  Affiliations Hospital for Sick Children, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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• Alla Gagarinova ,

  Contributed equally to this work with: Mohan Babu, Roland Arnold, Cedoljub Bundalovic-Torma, Alla Gagarinova, Keith S. Wong

  Affiliations Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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• Keith S. Wong ,

  Contributed equally to this work with: Mohan Babu, Roland Arnold, Cedoljub Bundalovic-Torma, Alla Gagarinova, Keith S. Wong

  Affiliation Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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• Ashwani Kumar,

  Affiliation Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada

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• Geordie Stewart,

  Affiliation Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

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• Bahram Samanfar,

  Affiliation Department of Biology and Ottawa Institute of Systems Biology, Carleton University, Ottawa, Ontario, Canada

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• Hiroyuki Aoki,

  Affiliation Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada

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• Omar Wagih,

  Affiliation Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada

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• James Vlasblom,

  Affiliation Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada

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• Sadhna Phanse,

  Affiliations Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada

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• Krunal Lad,

  Affiliation Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada

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• Angela Yeou Hsiung Yu,

  Affiliation Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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• Christopher Graham,

  Affiliation Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada

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• Ke Jin,

  Affiliations Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada

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• Eric Brown,

  Affiliation Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

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• Ashkan Golshani,

  Affiliation Department of Biology and Ottawa Institute of Systems Biology, Carleton University, Ottawa, Ontario, Canada

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• Philip Kim,

  Affiliation Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada

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• Gabriel Moreno-Hagelsieb,

  Affiliation Department of Biology, Wilfrid Laurier University, Waterloo, Ontario, Canada

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• Jack Greenblatt,

  Affiliations Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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• Walid A. Houry,

  Affiliation Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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• John Parkinson,

  Affiliations Hospital for Sick Children, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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•  [ ... ],
• Andrew Emili

  * E-mail: mohan.babu@uregina.ca (MB); andrew.emili@utoronto.ca (AE)

  Affiliations Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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