Canine Hereditary Ataxia in Old English Sheepdogs and Gordon Setters Is Associated with a Defect in the Autophagy Gene Encoding RAB24

Caryline Agler; Dahlia M. Nielsen; Ganokon Urkasemsin; Andrew Singleton; Noriko Tonomura; Snaevar Sigurdsson; Ruqi Tang; Keith Linder; Sampath Arepalli; Dena Hernandez; Kerstin Lindblad-Toh; Joyce van de Leemput; Alison Motsinger-Reif; Dennis P. O'Brien; Jerold Bell; Tonya Harris; Steven Steinberg; Natasha J. Olby

doi:10.1371/journal.pgen.1003991

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Research Article

Canine Hereditary Ataxia in Old English Sheepdogs and Gordon Setters Is Associated with a Defect in the Autophagy Gene Encoding RAB24

Caryline Agler,

Affiliation Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Dahlia M. Nielsen,

Affiliation Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Ganokon Urkasemsin,

Affiliation Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Andrew Singleton,

Affiliation Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, United States of America
⨯
Noriko Tonomura,

Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, United States of America
⨯
Snaevar Sigurdsson,

Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America
⨯
Ruqi Tang,

Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America
⨯
Keith Linder,

Affiliation Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Sampath Arepalli,

Affiliation Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, United States of America
⨯
Dena Hernandez,

Affiliation Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, United States of America
⨯
Kerstin Lindblad-Toh,

Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
⨯
Joyce van de Leemput,

Affiliation Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, United States of America
⨯
Alison Motsinger-Reif,

Affiliations Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America, Center for Comparative Medicine and Translational Research, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Dennis P. O'Brien,

Affiliation Department of Veterinary Medicine & Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, United States of America
⨯
Jerold Bell,

Affiliation Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, United States of America
⨯
Tonya Harris,

Affiliation Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Steven Steinberg,

Affiliation VCA Veterinary Referral Associates, Gaithersbrug, Maryland, United States of America
⨯
[ ... ],
Natasha J. Olby

* E-mail: Natasha_olby@ncsu.edu

Affiliations Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States of America, Center for Comparative Medicine and Translational Research, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
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Canine Hereditary Ataxia in Old English Sheepdogs and Gordon Setters Is Associated with a Defect in the Autophagy Gene Encoding RAB24

Caryline Agler,
Dahlia M. Nielsen,
Ganokon Urkasemsin,
Andrew Singleton,
Noriko Tonomura,
Snaevar Sigurdsson,
Ruqi Tang,
Keith Linder,
Sampath Arepalli,
Dena Hernandez

Published: February 6, 2014
https://doi.org/10.1371/journal.pgen.1003991

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21 Apr 2015
11:06 GMT
Most Recent

Figure 2E is not correct Posted by mavpouck on 21 Apr 2015 at 11:06 GMT

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