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Open Access
Peer-reviewed
Research Article
Targeted Ablation of Crb1 and Crb2 in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis
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Lucie P. Pellissier,
Affiliation Department of Neuromedical Genetics, The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands
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Celso Henrique Alves,
Affiliation Department of Neuromedical Genetics, The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands
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Peter M. Quinn,
Affiliation Department of Neuromedical Genetics, The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands
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Rogier M. Vos,
Affiliation Department of Neuromedical Genetics, The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands
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Naoyuki Tanimoto,
Affiliation Division of Ocular Neurodegeneration, Institute for Ophthalmic Research, Centre for Ophthalmology, Eberhard Karls University of Tübingen, Tübingen, Germany
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Ditte M. S. Lundvig,
Affiliation Department of Neuromedical Genetics, The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands
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Jacobus J. Dudok,
Affiliation Department of Neuromedical Genetics, The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands
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Berend Hooibrink,
Affiliation Department of Cell Biology and Histology, Amsterdam Medisch Centrum, Amsterdam, The Netherlands
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Fabrice Richard,
Affiliation Aix-Marseille University, Developmental Biology Institute of Marseille Luminy (IBDML) and CNRS, UMR 6216, Marseille, France
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Susanne C. Beck,
Affiliation Division of Ocular Neurodegeneration, Institute for Ophthalmic Research, Centre for Ophthalmology, Eberhard Karls University of Tübingen, Tübingen, Germany
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Gesine Huber,
Affiliation Division of Ocular Neurodegeneration, Institute for Ophthalmic Research, Centre for Ophthalmology, Eberhard Karls University of Tübingen, Tübingen, Germany
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Vithiyanjali Sothilingam,
Affiliation Division of Ocular Neurodegeneration, Institute for Ophthalmic Research, Centre for Ophthalmology, Eberhard Karls University of Tübingen, Tübingen, Germany
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Marina Garcia Garrido,
Affiliation Division of Ocular Neurodegeneration, Institute for Ophthalmic Research, Centre for Ophthalmology, Eberhard Karls University of Tübingen, Tübingen, Germany
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André Le Bivic,
Affiliation Aix-Marseille University, Developmental Biology Institute of Marseille Luminy (IBDML) and CNRS, UMR 6216, Marseille, France
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Mathias W. Seeliger,
Affiliation Division of Ocular Neurodegeneration, Institute for Ophthalmic Research, Centre for Ophthalmology, Eberhard Karls University of Tübingen, Tübingen, Germany
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Jan Wijnholds
* E-mail: j.wijnholds@nin.knaw.nl
Affiliation Department of Neuromedical Genetics, The Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The Netherlands
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Targeted Ablation of Crb1 and Crb2 in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis
- Lucie P. Pellissier,
- Celso Henrique Alves,
- Peter M. Quinn,
- Rogier M. Vos,
- Naoyuki Tanimoto,
- Ditte M. S. Lundvig,
- Jacobus J. Dudok,
- Berend Hooibrink,
- Fabrice Richard,
- Susanne C. Beck
- Published: December 5, 2013
- https://doi.org/10.1371/journal.pgen.1003976