Genetic and Functional Studies Implicate Synaptic Overgrowth and Ring Gland cAMP/PKA Signaling Defects in the Drosophila melanogaster Neurofibromatosis-1 Growth Deficiency

• James A. Walker,

  Affiliations Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Jean Y. Gouzi,

  Current address: Institute of Cellular and Developmental Biology, Biomedical Sciences Research Centre “Alexander Fleming,” Vari, Greece.

  Affiliation Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts, United States of America

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• Jennifer B. Long,

  Affiliation Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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• Sidong Huang,

  Current address: Department of Biochemistry, McIntyre Medical Building, Montreal, Quebec, Canada.

  Affiliation Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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• Robert C. Maher,

  Affiliation Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts, United States of America

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• Hongjing Xia,

  Affiliation Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts, United States of America

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• Kheyal Khalil,

  Affiliation Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts, United States of America

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• Arjun Ray,

  Affiliation Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts, United States of America

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• David Van Vactor,

  Affiliation Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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• René Bernards,

  Affiliation Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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• André Bernards

  * E-mail: abernards@helix.mgh.harvard.edu

  Current address: Department of Biochemistry, McIntyre Medical Building, Montreal, Quebec, Canada.

  Affiliations Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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