Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

Fang Han; Juliette Faraco; Xiao Song Dong; Hanna M. Ollila; Ling Lin; Jing Li; Pei An; Shan Wang; Ke Wei Jiang; Zhan Cheng Gao; Long Zhao; Han Yan; Ya Nan Liu; Qing Hua Li; Xiao Zhe Zhang; Yan Hu; Jing Yu Wang; Yun Hui Lu; Chang Jun Lu; Wei Zhou; Joachim Hallmayer; Yu Shu Huang; Kingman P. Strohl; Thomas Pollmächer; Emmanuel Mignot

doi:10.1371/journal.pgen.1003880

Loading metrics

Open Access

Peer-reviewed

Research Article

Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

Fang Han ,

* E-mail: hanfang1@hotmail.com (FH); mignot@stanford.edu (EM)

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Juliette Faraco,

Affiliation Stanford University Center for Sleep Sciences, Palo Alto, California, United States
⨯
Xiao Song Dong,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Hanna M. Ollila,

Affiliation Stanford University Center for Sleep Sciences, Palo Alto, California, United States
⨯
Ling Lin,

Affiliation Stanford University Center for Sleep Sciences, Palo Alto, California, United States
⨯
Jing Li,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Pei An,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Shan Wang,

Affiliation Department of Surgery, Peking University People's Hospital, Beijing, China
⨯
Ke Wei Jiang,

Affiliation Department of Surgery, Peking University People's Hospital, Beijing, China
⨯
Zhan Cheng Gao,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Long Zhao,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Han Yan,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Ya Nan Liu,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Qing Hua Li,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Xiao Zhe Zhang,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Yan Hu,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Jing Yu Wang,

Affiliation Department of Pulmonary Medicine, Bin Zhou Medical University, Shandong, China
⨯
Yun Hui Lu,

Affiliation Department of Pulmonary Medicine, Yun Nan Province Hospital, Yun Nan, China
⨯
Chang Jun Lu,

Affiliation Department of Pulmonary Medicine, Bin Zhou Medical University, Shandong, China
⨯
Wei Zhou,

Affiliation Department of Pulmonary, Critical Care Medicine, Peking University People's Hospital, Beijing, China
⨯
Joachim Hallmayer,

Affiliation Stanford University Center for Sleep Sciences, Palo Alto, California, United States
⨯
Yu Shu Huang,

Affiliation National Taiwan University, Taiwan, China
⨯
Kingman P. Strohl,

Affiliation Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Case Western Reserve University, and Cleveland Louis Stokes VA Medical Center, Cleveland, Ohio, United States
⨯
Thomas Pollmächer,

Affiliation Center of Mental Health, Ingolstadt, Klinikum Ingolstadt, Krumenauerstrasse, Ingolstadt, Germany
⨯
[ ... ],
Emmanuel Mignot

* E-mail: hanfang1@hotmail.com (FH); mignot@stanford.edu (EM)

Affiliation Stanford University Center for Sleep Sciences, Palo Alto, California, United States
⨯
[ view all ]
[ view less ]

Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

Fang Han,
Juliette Faraco,
Xiao Song Dong,
Hanna M. Ollila,
Ling Lin,
Jing Li,
Pei An,
Shan Wang,
Ke Wei Jiang,
Zhan Cheng Gao

Published: October 31, 2013
https://doi.org/10.1371/journal.pgen.1003880

Reader Comments (2)

Post a new comment on this article

0 Responses

13 Dec 2013
14:49 GMT
Most Recent

Publisher's Note: Acknowledgments incorrect Posted by PLOS_Genetics on 13 Dec 2013 at 14:49 GMT
0 Responses

08 Nov 2013
12:37 GMT
Most Recent

Publisher's Note: Error in affiliation Posted by PLOS_Genetics on 08 Nov 2013 at 12:37 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Narcolepsy
Is the Subject Area "Narcolepsy" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Genetic loci
Is the Subject Area "Genetic loci" applicable to this article?

Thanks for your feedback.
Genome-wide association studies
Is the Subject Area "Genome-wide association studies" applicable to this article?

Thanks for your feedback.
T cell receptors
Is the Subject Area "T cell receptors" applicable to this article?

Thanks for your feedback.
Haplotypes
Is the Subject Area "Haplotypes" applicable to this article?

Thanks for your feedback.
Europe
Is the Subject Area "Europe" applicable to this article?

Thanks for your feedback.
Sleep
Is the Subject Area "Sleep" applicable to this article?

Thanks for your feedback.