Removal of Misincorporated Ribonucleotides from Prokaryotic Genomes: An Unexpected Role for Nucleotide Excision Repair

Alexandra Vaisman; John P. McDonald; Donald Huston; Wojciech Kuban; Lili Liu; Bennett Van Houten; Roger Woodgate

doi:10.1371/journal.pgen.1003878

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Open Access

Peer-reviewed

Research Article

Removal of Misincorporated Ribonucleotides from Prokaryotic Genomes: An Unexpected Role for Nucleotide Excision Repair

Alexandra Vaisman,

Affiliation Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
John P. McDonald,

Affiliation Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Donald Huston,

Affiliation Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Wojciech Kuban,

Current address: Laboratory of NF-kB Signaling, Institute of Molecular and Cell Biology (IMCB), Proteos, Singapore, Singapore.

Affiliation Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Lili Liu,

Affiliation Department of Pharmacology and Chemical Biology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
⨯
Bennett Van Houten,

Affiliation Department of Pharmacology and Chemical Biology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
⨯
Roger Woodgate

* E-mail: woodgate@nih.gov

Affiliation Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Removal of Misincorporated Ribonucleotides from Prokaryotic Genomes: An Unexpected Role for Nucleotide Excision Repair

Alexandra Vaisman,
John P. McDonald,
Donald Huston,
Wojciech Kuban,
Lili Liu,
Bennett Van Houten,
Roger Woodgate

Published: November 7, 2013
https://doi.org/10.1371/journal.pgen.1003878

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Ribonucleotides
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Ribonucleases
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Mutagenesis
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DNA repair
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Genomics
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DNA polymerase
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Mismatch repair
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Genetics
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