Cooperative Interaction between Phosphorylation Sites on PERIOD Maintains Circadian Period in Drosophila

David S. Garbe; Yanshan Fang; Xiangzhong Zheng; Mallory Sowcik; Rana Anjum; Steven P. Gygi; Amita Sehgal

doi:10.1371/journal.pgen.1003749

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Peer-reviewed

Research Article

Cooperative Interaction between Phosphorylation Sites on PERIOD Maintains Circadian Period in Drosophila

David S. Garbe,

Affiliation Department of Neuroscience, University of Pennsylvania School of Medicine, Translational Research Center, Philadelphia, Pennsylvania, United States of America
⨯
Yanshan Fang,

Current address: Howard Hughes Medical Institute, Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

Affiliation Department of Neuroscience, University of Pennsylvania School of Medicine, Translational Research Center, Philadelphia, Pennsylvania, United States of America
⨯
Xiangzhong Zheng,

Affiliation Department of Neuroscience, University of Pennsylvania School of Medicine, Translational Research Center, Philadelphia, Pennsylvania, United States of America
⨯
Mallory Sowcik,

Affiliation Department of Neuroscience, University of Pennsylvania School of Medicine, Translational Research Center, Philadelphia, Pennsylvania, United States of America
⨯
Rana Anjum,

Current address: ARIAD Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America.

Affiliation Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Steven P. Gygi,

Affiliation Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Amita Sehgal

* E-mail: amita@mail.med.upenn.edu

Affiliations Department of Neuroscience, University of Pennsylvania School of Medicine, Translational Research Center, Philadelphia, Pennsylvania, United States of America, Howard Hughes Medical Institute, University of Pennsylvania School of Medicine, Translational Research Center, Philadelphia, Pennsylvania, United States of America
⨯

Cooperative Interaction between Phosphorylation Sites on PERIOD Maintains Circadian Period in Drosophila

David S. Garbe,
Yanshan Fang,
Xiangzhong Zheng,
Mallory Sowcik,
Rana Anjum,
Steven P. Gygi,
Amita Sehgal

Published: September 26, 2013
https://doi.org/10.1371/journal.pgen.1003749

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Phosphorylation
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Drosophila melanogaster
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Circadian rhythms
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