GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm

• Leonardo Bottolo ,

  Contributed equally to this work with: Leonardo Bottolo, Marc Chadeau-Hyam

  * E-mail: l.bottolo@imperial.ac.uk (LB); sylvia@mrc-bsu.cam.ac.uk (SR)

  Affiliation Department of Mathematics, Imperial College London, London, United Kingdom

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• Marc Chadeau-Hyam ,

  Contributed equally to this work with: Leonardo Bottolo, Marc Chadeau-Hyam

  Affiliation Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom

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• David I. Hastie,

  Affiliation Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom

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• Tanja Zeller,

  Affiliation University Heart Center Hamburg, Department of General and Interventional Cardiology, Hamburg, Germany

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• Benoit Liquet,

  Affiliations INSERM U897, University Victor Segalen, Bordeaux, France, MRC Biostatistics Unit, Institute of Public Health, Cambridge, United Kingdom

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• Paul Newcombe,

  Affiliation MRC Biostatistics Unit, Institute of Public Health, Cambridge, United Kingdom

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• Loic Yengo,

  Affiliations European Genomic Institute for Diabetes, Lille, France, CNRS UMR 8199 - Institut Pasteur de Lille, Lille, France

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• Philipp S. Wild,

  Affiliation Clinical Epidemiology, Center for Thrombosis and Haemostasis, University Medical Center Mainz, Mainz, Germany

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• Arne Schillert,

  Affiliation Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany

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• Andreas Ziegler,

  Affiliation Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany

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• Sune F. Nielsen,

  Affiliations Department of Clinical Biochemistry, Herlev Hospital, Copenhagen, Denmark, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark

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• Adam S. Butterworth,

  Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• Weang Kee Ho,

  Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• Raphaële Castagné,

  Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6), Paris, France

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• Thomas Munzel,

  Affiliation Department of Medicine II, University Medical Center Mainz, Mainz, Germany

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• David Tregouet,

  Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• Mario Falchi,

  Affiliation Department of Genomics of Common Disease, School Of Public Health, Hammersmith Hospital, Imperial College London, London, United Kingdom

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• François Cambien,

  Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6), Paris, France

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• Børge G. Nordestgaard,

  Affiliations Department of Clinical Biochemistry, Herlev Hospital, Copenhagen, Denmark, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark

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• Fredéric Fumeron,

  Affiliations INSERM U695, Paris, France, Université Paris Diderot-Paris 7, UFR de Médecine Site Bichat, Paris, France

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• Anne Tybjærg-Hansen,

  Affiliation Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark

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• Philippe Froguel,

  Affiliations European Genomic Institute for Diabetes, Lille, France, CNRS UMR 8199 - Institut Pasteur de Lille, Lille, France, Department of Genomics of Common Disease, School Of Public Health, Hammersmith Hospital, Imperial College London, London, United Kingdom, Université de Lille 2, Lille, France

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• John Danesh,

  Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

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• Enrico Petretto,

  Affiliation Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, United Kingdom

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• Stefan Blankenberg,

  Affiliation University Heart Center Hamburg, Department of General and Interventional Cardiology, Hamburg, Germany

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• Laurence Tiret,

  Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6), Paris, France

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•  [ ... ],
• Sylvia Richardson

  * E-mail: l.bottolo@imperial.ac.uk (LB); sylvia@mrc-bsu.cam.ac.uk (SR)

  Affiliation MRC Biostatistics Unit, Institute of Public Health, Cambridge, United Kingdom

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