Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus

Clint L. Miller; D. Ryan Anderson; Ramendra K. Kundu; Azad Raiesdana; Sylvia T. Nürnberg; Roxanne Diaz; Karen Cheng; Nicholas J. Leeper; Chung-Hsing Chen; I-Shou Chang; Eric E. Schadt; Chao Agnes Hsiung; Themistocles L. Assimes; Thomas Quertermous

doi:10.1371/journal.pgen.1003652

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Open Access

Peer-reviewed

Research Article

Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus

Clint L. Miller ,

* E-mail: clintm@stanford.edu (CLM); tomq1@stanford.edu (TQ)

Affiliation Department of Medicine, Division of Cardiovascular Medicine, and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America
⨯
D. Ryan Anderson,

Affiliation Department of Medicine, Division of Cardiovascular Medicine, and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Ramendra K. Kundu,

Affiliation Department of Medicine, Division of Cardiovascular Medicine, and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Azad Raiesdana,

Affiliation Department of Medicine, Division of Cardiovascular Medicine, and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Sylvia T. Nürnberg,

Affiliation Department of Medicine, Division of Cardiovascular Medicine, and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Roxanne Diaz,

Affiliation Department of Medicine, Division of Cardiovascular Medicine, and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Karen Cheng,

Affiliation Department of Medicine, Division of Cardiovascular Medicine, and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Nicholas J. Leeper,

Affiliations Department of Medicine, Division of Cardiovascular Medicine, and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America, Department of Surgery, Division of Vascular Surgery, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Chung-Hsing Chen,

Affiliation Division of Biostatistics and Bioinformatics, National Health Research Institutes, Zhunan, Taiwan
⨯
I-Shou Chang,

Affiliation Division of Biostatistics and Bioinformatics, National Health Research Institutes, Zhunan, Taiwan
⨯
Eric E. Schadt,

Affiliation Institute for Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, New York, United States of America
⨯
Chao Agnes Hsiung,

Affiliation Division of Biostatistics and Bioinformatics, National Health Research Institutes, Zhunan, Taiwan
⨯
Themistocles L. Assimes,

Affiliation Department of Medicine, Division of Cardiovascular Medicine, and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Thomas Quertermous

* E-mail: clintm@stanford.edu (CLM); tomq1@stanford.edu (TQ)

Affiliation Department of Medicine, Division of Cardiovascular Medicine, and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, United States of America
⨯

Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus

Clint L. Miller,
D. Ryan Anderson,
Ramendra K. Kundu,
Azad Raiesdana,
Sylvia T. Nürnberg,
Roxanne Diaz,
Karen Cheng,
Nicholas J. Leeper,
Chung-Hsing Chen,
I-Shou Chang

Published: July 18, 2013
https://doi.org/10.1371/journal.pgen.1003652

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