The Wilms Tumor Gene, Wt1, Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans

• Xiao Na Wang ,

  Contributed equally to this work with: Xiao Na Wang, Ze Song Li, Yu Ren, Tao Jiang

  Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, University of Chinese Academy of Sciences, Beijing, China

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• Ze Song Li ,

  Contributed equally to this work with: Xiao Na Wang, Ze Song Li, Yu Ren, Tao Jiang

  Affiliations Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, China, Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen, China

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• Yu Ren ,

  Contributed equally to this work with: Xiao Na Wang, Ze Song Li, Yu Ren, Tao Jiang

  Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, University of Chinese Academy of Sciences, Beijing, China

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• Tao Jiang ,

  Contributed equally to this work with: Xiao Na Wang, Ze Song Li, Yu Ren, Tao Jiang

  Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China

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• Ya Qing Wang,

  Affiliation Key Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

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• Min Chen,

  Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

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• Jun Zhang,

  Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, University of Chinese Academy of Sciences, Beijing, China

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• Jian Xiu Hao,

  Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, University of Chinese Academy of Sciences, Beijing, China

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• Yan Bo Wang,

  Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, University of Chinese Academy of Sciences, Beijing, China

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• Ri Na Sha,

  Affiliations State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China, University of Chinese Academy of Sciences, Beijing, China

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• Yi Huang,

  Affiliations Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, China, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen, China

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• Xiao Liu,

  Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China

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• Jing Chu Hu,

  Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China

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• Guang Qing Sun,

  Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China

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• Hong Gang Li,

  Affiliation Center of Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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• Cheng Liang Xiong,

  Affiliation Center of Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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• Jun Xie,

  Affiliation Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, China

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• Zhi Mao Jiang,

  Affiliation Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, China

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• Zhi Ming Cai,

  Affiliations Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, China, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen, China

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• Jun Wang,

  Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China

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• Jian Wang,

  Affiliation Beijing Genomics Institute at Shenzhen, Shenzhen, China

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• Vicki Huff ,

  * E-mail: vhuff@mdanderson.org (VH); guiyaoting2007@yahoo.com.cn (YTG); gaof@ioz.ac.cn (FG)

  Affiliation Department of Genetics, The University of Texas M. D. Anderson Cancer Center; Graduate Programs in Human Molecular Genetics and Genes and Development, University of Texas, Houston, Texas, United States of America

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• Yao Ting Gui ,

  * E-mail: vhuff@mdanderson.org (VH); guiyaoting2007@yahoo.com.cn (YTG); gaof@ioz.ac.cn (FG)

  Affiliation Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, China

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•  [ ... ],
• Fei Gao

  * E-mail: vhuff@mdanderson.org (VH); guiyaoting2007@yahoo.com.cn (YTG); gaof@ioz.ac.cn (FG)

  Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

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