The BTB-zinc Finger Transcription Factor Abrupt Acts as an Epithelial Oncogene in Drosophila melanogaster through Maintaining a Progenitor-like Cell State

• Nezaket Turkel,

  Affiliations Cell Cycle and Development Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, Department of Anatomy and Cell Biology, The University of Melbourne, Melbourne, Victoria, Australia

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• Virender K. Sahota,

  Affiliation Cell Cycle and Development Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

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• Jessica E. Bolden,

  Affiliation Cell Cycle and Development Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

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• Karen R. Goulding,

  Affiliation Cell Cycle and Development Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

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• Karen Doggett,

  Affiliation Cell Cycle and Development Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

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• Lee F. Willoughby,

  Affiliation Cell Cycle and Development Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

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• Enrique Blanco,

  Affiliation Departament de Genètica i Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Spain

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• Enrique Martin-Blanco,

  Affiliation Instituto de Biología Molecular de Barcelona (CSIC), Parc Cientific de Barcelona, Barcelona, Spain

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• Montserrat Corominas,

  Affiliation Departament de Genètica i Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Spain

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• Jason Ellul,

  Affiliation Bioinformatics Core Facility, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

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• Toshiro Aigaki,

  Affiliation Department of Biological Sciences, Tokyo Metropolitan University, Hachioji, Tokyo, Japan

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• Helena E. Richardson ,

  * E-mail: helena.richardson@petermac.org

  ¶Co-senior authors.

  Affiliations Cell Cycle and Development Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, Department of Anatomy and Cell Biology, The University of Melbourne, Melbourne, Victoria, Australia, Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia, Department of Biochemistry and Molecular Biology, University of Melbourne, Melbourne, Victoria, Australia

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• Anthony M. Brumby

  ¶Co-senior authors.

  Affiliations Cell Cycle and Development Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, Department of Anatomy and Cell Biology, The University of Melbourne, Melbourne, Victoria, Australia, Department of Genetics, The University of Melbourne, Melbourne, Victoria, Australia

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