ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice

• Lois Kelsey,

  Affiliations Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada, Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada

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• Ann M. Flenniken,

  Affiliations Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada, Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada

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• Dawei Qu,

  Affiliations Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada, Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada

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• Alister P. W. Funnell,

  Affiliation School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia

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• Richard Pearson,

  Affiliation School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia

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• Yu-Qing Zhou,

  Affiliations Mouse Imaging Centre, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada

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• Irina Voronina,

  Affiliations Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada, Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada

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• Zorana Berberovic,

  Affiliations Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada, Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada

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• Geoffrey Wood,

  Affiliations Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada

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• Susan Newbigging,

  Affiliations Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada

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• Edward S. Weiss,

  Affiliation Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada

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• Michael Wong,

  Affiliations Mouse Imaging Centre, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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• Ivan Quach,

  Affiliation Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada

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• S. Y. Sandy Yeh,

  Affiliation Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada

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• Ashish R. Deshwar,

  Affiliations The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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• Ian C. Scott,

  Affiliations The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Heart and Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada

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• Colin McKerlie,

  Affiliations Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada

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• Mark Henkelman,

  Affiliations Mouse Imaging Centre, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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• Peter Backx,

  Affiliations Heart and Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada, Department of Physiology, University of Toronto, Toronto, Ontario, Canada

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• Jeremy Simpson,

  Affiliations Heart and Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada, Department of Physiology, University of Toronto, Toronto, Ontario, Canada

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• Lucy Osborne,

  Affiliations Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

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• Janet Rossant,

  Affiliations Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada

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• Merlin Crossley,

  Affiliation School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia

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• Benoit Bruneau,

  Affiliation Gladstone Institute of Cardiovascular Disease, Department of Pediatrics, and Cardiovascular Research Institute, University of California, San Francisco, California, United States of America

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•  [ ... ],
• S. Lee Adamson

  * E-mail: adamson@lunenfeld.ca

  Affiliations Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada, Centre for Modeling Human Disease, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, Heart and Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada, Department of Physiology, University of Toronto, Toronto, Ontario, Canada, Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada

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