NSAIDs Modulate Clonal Evolution in Barrett's Esophagus

Rumen L. Kostadinov; Mary K. Kuhner; Xiaohong Li; Carissa A. Sanchez; Patricia C. Galipeau; Thomas G. Paulson; Cassandra L. Sather; Amitabh Srivastava; Robert D. Odze; Patricia L. Blount; Thomas L. Vaughan; Brian J. Reid; Carlo C. Maley

doi:10.1371/journal.pgen.1003553

Loading metrics

Open Access

Peer-reviewed

Research Article

NSAIDs Modulate Clonal Evolution in Barrett's Esophagus

Rumen L. Kostadinov,

Affiliations Genomics and Computational Biology Graduate Program, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, The Wistar Institute, Philadelphia, Pennsylvania, United States of America, Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
⨯
Mary K. Kuhner,

Affiliation Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America
⨯
Xiaohong Li,

Affiliations Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Carissa A. Sanchez,

Affiliations Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Patricia C. Galipeau,

Affiliations Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Thomas G. Paulson,

Affiliations Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Cassandra L. Sather,

Affiliation Genomics Resource, DNA Array Laboratory, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Amitabh Srivastava,

Affiliation Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Robert D. Odze,

Affiliation Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Patricia L. Blount,

Affiliations Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Thomas L. Vaughan,

Affiliation Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Brian J. Reid,

Affiliations Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America, Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America
⨯
Carlo C. Maley

* E-mail: cmaley@alum.mit.edu

Affiliations Genomics and Computational Biology Graduate Program, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, The Wistar Institute, Philadelphia, Pennsylvania, United States of America, Center for Evolution and Cancer, Helen Diller Family Comprehensive Cancer Center, Department of Surgery, University of California San Francisco, San Francisco, California, United States of America
⨯

NSAIDs Modulate Clonal Evolution in Barrett's Esophagus

Rumen L. Kostadinov,
Mary K. Kuhner,
Xiaohong Li,
Carissa A. Sanchez,
Patricia C. Galipeau,
Thomas G. Paulson,
Cassandra L. Sather,
Amitabh Srivastava,
Robert D. Odze,
Patricia L. Blount

Published: June 13, 2013
https://doi.org/10.1371/journal.pgen.1003553

Reader Comments (2)

Post a new comment on this article

0 Responses

20 Jun 2013
15:27 GMT
Most Recent

Response to jamesmhoward Posted by rkostadi on 20 Jun 2013 at 15:27 GMT
0 Responses

20 Jun 2013
13:29 GMT
Most Recent

Aspirin Reduces Testosterone which may Increase Mutations Posted by jamesmhoward on 20 Jun 2013 at 13:29 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Biopsy
Is the Subject Area "Biopsy" applicable to this article?

Thanks for your feedback.
NSAIDs
Is the Subject Area "NSAIDs" applicable to this article?

Thanks for your feedback.
Phylogenetic analysis
Is the Subject Area "Phylogenetic analysis" applicable to this article?

Thanks for your feedback.
Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.
Endoscopy
Is the Subject Area "Endoscopy" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Phylogenetics
Is the Subject Area "Phylogenetics" applicable to this article?

Thanks for your feedback.