Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy

Nathalie Caruso; Balàzs Herberth; Marc Bartoli; Francesca Puppo; Julie Dumonceaux; Angela Zimmermann; Simon Denadai; Marie Lebossé; Stephane Roche; Linda Geng; Frederique Magdinier; Shahram Attarian; Rafaelle Bernard; Flavio Maina; Nicolas Levy; Françoise Helmbacher

doi:10.1371/journal.pgen.1003550

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Research Article

Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy

Nathalie Caruso,

Affiliation Aix-Marseille Université, CNRS, IBDML UMR 7288, Parc Scientifique de Luminy, Case 907, Marseille, France
⨯
Balàzs Herberth,

Affiliation Aix-Marseille Université, CNRS, IBDML UMR 7288, Parc Scientifique de Luminy, Case 907, Marseille, France
⨯
Marc Bartoli,

Affiliation Aix-Marseille Université, Faculté de Médecine de la Timone, INSERM UMR 910, Marseille, France
⨯
Francesca Puppo,

Affiliation Aix-Marseille Université, Faculté de Médecine de la Timone, INSERM UMR 910, Marseille, France
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Julie Dumonceaux,

Affiliation INSERM U974, UMR 7215 CNRS, Institut de Myologie, UM 76 Université Pierre et Marie Curie, Paris, France
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Angela Zimmermann,

Affiliation Aix-Marseille Université, CNRS, IBDML UMR 7288, Parc Scientifique de Luminy, Case 907, Marseille, France
⨯
Simon Denadai,

Affiliation Aix-Marseille Université, CNRS, IBDML UMR 7288, Parc Scientifique de Luminy, Case 907, Marseille, France
⨯
Marie Lebossé,

Affiliation Aix-Marseille Université, CNRS, IBDML UMR 7288, Parc Scientifique de Luminy, Case 907, Marseille, France
⨯
Stephane Roche,

Affiliation Aix-Marseille Université, Faculté de Médecine de la Timone, INSERM UMR 910, Marseille, France
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Linda Geng,

Affiliation Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Frederique Magdinier,

Affiliation Aix-Marseille Université, Faculté de Médecine de la Timone, INSERM UMR 910, Marseille, France
⨯
Shahram Attarian,

Affiliations Aix-Marseille Université, Faculté de Médecine de la Timone, INSERM UMR 910, Marseille, France, AP-HM, Neurologie, maladies neuro-musculaires, Hôpital de la Timone, Marseille, France
⨯
Rafaelle Bernard,

Affiliations Aix-Marseille Université, Faculté de Médecine de la Timone, INSERM UMR 910, Marseille, France, AP-HM, Département de Génétique Médicale, Hôpital d'enfants Timone, Marseille, France
⨯
Flavio Maina,

Affiliation Aix-Marseille Université, CNRS, IBDML UMR 7288, Parc Scientifique de Luminy, Case 907, Marseille, France
⨯
Nicolas Levy,

Affiliations Aix-Marseille Université, Faculté de Médecine de la Timone, INSERM UMR 910, Marseille, France, AP-HM, Département de Génétique Médicale, Hôpital d'enfants Timone, Marseille, France
⨯
[ ... ],
Françoise Helmbacher

* E-mail: Francoise.HELMBACHER@univ-amu.fr

Affiliation Aix-Marseille Université, CNRS, IBDML UMR 7288, Parc Scientifique de Luminy, Case 907, Marseille, France
⨯
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Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy

Nathalie Caruso,
Balàzs Herberth,
Marc Bartoli,
Francesca Puppo,
Julie Dumonceaux,
Angela Zimmermann,
Simon Denadai,
Marie Lebossé,
Stephane Roche,
Linda Geng

Published: June 13, 2013
https://doi.org/10.1371/journal.pgen.1003550

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Myoblasts
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Facioscapulohumeral muscular dystrophy
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