CDK4 T172 Phosphorylation Is Central in a CDK7-Dependent Bidirectional CDK4/CDK2 Interplay Mediated by p21 Phosphorylation at the Restriction Point

Open Access

Peer-reviewed

Research Article

Xavier Bisteau ,

Contributed equally to this work with: Xavier Bisteau, Sabine Paternot

Affiliation WELBIO and Institute of Interdisciplinary Research (IRIBHM), Université Libre de Bruxelles, Brussels, Belgium
⨯
Sabine Paternot ,

Contributed equally to this work with: Xavier Bisteau, Sabine Paternot

Affiliation WELBIO and Institute of Interdisciplinary Research (IRIBHM), Université Libre de Bruxelles, Brussels, Belgium
⨯
Bianca Colleoni,

Affiliation WELBIO and Institute of Interdisciplinary Research (IRIBHM), Université Libre de Bruxelles, Brussels, Belgium
⨯
Karin Ecker,

Affiliation Division of Medical Biochemistry, Biocenter, Innsbruck Medical University, Innsbruck, Austria
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Katia Coulonval,

Affiliation WELBIO and Institute of Interdisciplinary Research (IRIBHM), Université Libre de Bruxelles, Brussels, Belgium
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Philippe De Groote,

Affiliation Department for Molecular Biomedical Research, VIB, and Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium
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Wim Declercq,

Affiliation Department for Molecular Biomedical Research, VIB, and Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium
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Ludger Hengst,

Affiliation Division of Medical Biochemistry, Biocenter, Innsbruck Medical University, Innsbruck, Austria
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Pierre P. Roger

* E-mail: proger@ulb.ac.be

Affiliation WELBIO and Institute of Interdisciplinary Research (IRIBHM), Université Libre de Bruxelles, Brussels, Belgium
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Phosphorylation
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Cyclins
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Immunoprecipitation
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Two-dimensional gel electrophoresis
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CHO cells
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Immunodetection
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Transfection
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Cell cycle and cell division
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