Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits

Noah Zaitlen; Peter Kraft; Nick Patterson; Bogdan Pasaniuc; Gaurav Bhatia; Samuela Pollack; Alkes L. Price

doi:10.1371/journal.pgen.1003520

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Peer-reviewed

Research Article

Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits

Noah Zaitlen ,

* E-mail: noah.zaitlen@ucsf.edu (NZ); aprice@hsph.harvard.edu (ALP)

Affiliation Department of Medicine, Lung Biology Center, University of California San Francisco, San Francisco, California, United States of America
⨯
Peter Kraft,

Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Nick Patterson,

Affiliation Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Bogdan Pasaniuc,

Affiliation Interdepartmental Program in Bioinformatics Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, California, United States of America
⨯
Gaurav Bhatia,

Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Samuela Pollack,

Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Alkes L. Price

* E-mail: noah.zaitlen@ucsf.edu (NZ); aprice@hsph.harvard.edu (ALP)

Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯

Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits

Noah Zaitlen,
Peter Kraft,
Nick Patterson,
Bogdan Pasaniuc,
Gaurav Bhatia,
Samuela Pollack,
Alkes L. Price

Published: May 30, 2013
https://doi.org/10.1371/journal.pgen.1003520

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