Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

• Joshua C. Randall ,

  Contributed equally to this work with: Joshua C. Randall, Thomas W. Winkler, Zoltán Kutalik, Sonja I. Berndt

  Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

  ⨯
• Thomas W. Winkler ,

  Contributed equally to this work with: Joshua C. Randall, Thomas W. Winkler, Zoltán Kutalik, Sonja I. Berndt

  Affiliation Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany

  ⨯
• Zoltán Kutalik ,

  Contributed equally to this work with: Joshua C. Randall, Thomas W. Winkler, Zoltán Kutalik, Sonja I. Berndt

  Affiliations Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland

  ⨯
• Sonja I. Berndt ,

  Contributed equally to this work with: Joshua C. Randall, Thomas W. Winkler, Zoltán Kutalik, Sonja I. Berndt

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America

  ⨯
• Anne U. Jackson,

  Affiliation Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Keri L. Monda,

  Affiliation Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  ⨯
• Tuomas O. Kilpeläinen,

  Affiliation MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

  ⨯
• Tõnu Esko,

  Affiliations Estonian Genome Center, University of Tartu, Tartu, Estonia, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

  ⨯
• Reedik Mägi,

  Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Estonian Genome Center, University of Tartu, Tartu, Estonia

  ⨯
• Shengxu Li,

  Affiliations MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom, Department of Epidemiology, Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of America

  ⨯
• Tsegaselassie Workalemahu,

  Affiliation Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America

  ⨯
• Mary F. Feitosa,

  Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• Damien C. Croteau-Chonka,

  Affiliation Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America

  ⨯
• Felix R. Day,

  Affiliation MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

  ⨯
• Tove Fall,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

  ⨯
• Teresa Ferreira,

  Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

  ⨯
• Stefan Gustafsson,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

  ⨯
• Adam E. Locke,

  Affiliation Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Iain Mathieson,

  Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

  ⨯
• Andre Scherag,

  Affiliation Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital of Essen, University of Duisburg-Essen, Essen, Germany

  ⨯
• Sailaja Vedantam,

  Affiliations Divisions of Genetics and Endocrinology and Program in Genomics, Children's Hospital, Boston, Massachusetts, United States of America, Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Andrew R. Wood,

  Affiliation Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom

  ⨯
• Liming Liang,

  Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

  ⨯
• Valgerdur Steinthorsdottir,

  Affiliation deCODE Genetics, Reykjavik, Iceland

  ⨯
• Gudmar Thorleifsson,

  Affiliation deCODE Genetics, Reykjavik, Iceland

  ⨯
• Emmanouil T. Dermitzakis,

  Affiliation Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland

  ⨯
• Antigone S. Dimas,

  Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Biomedical Sciences Research Center Al. Fleming, Vari, Greece

  ⨯
• Fredrik Karpe,

  Affiliation Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom

  ⨯
• Josine L. Min,

  Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

  ⨯
• George Nicholson,

  Affiliations Department of Statistics, University of Oxford, Oxford, United Kingdom, MRC Harwell, Harwell, United Kingdom

  ⨯
• Deborah J. Clegg,

  Affiliation University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

  ⨯
• Thomas Person,

  Affiliation University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

  ⨯
• Jon P. Krohn,

  Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

  ⨯
• Sabrina Bauer,

  Affiliation Regensburg University Medical Center, Innere Medizin I, Regensburg, Germany

  ⨯
• Christa Buechler,

  Affiliation Regensburg University Medical Center, Innere Medizin I, Regensburg, Germany

  ⨯
• Kristina Eisinger,

  Affiliation Regensburg University Medical Center, Innere Medizin I, Regensburg, Germany

  ⨯
• DIAGRAM Consortium,
• Amélie Bonnefond,

  Affiliation CNRS UMR8199-IBL-Institut Pasteur de Lille, Lille, France

  ⨯
• Philippe Froguel,

  Affiliations CNRS UMR8199-IBL-Institut Pasteur de Lille, Lille, France, Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, United Kingdom

  ⨯
• MAGIC Investigators,
• Jouke-Jan Hottenga,

  Affiliation Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands

  ⨯
• Inga Prokopenko,

  Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom

  ⨯
• Lindsay L. Waite,

  Affiliation Hudson Alpha Institute for Biotechnology, Huntsville, Alabama, United States of America

  ⨯
• Tamara B. Harris,

  Affiliation Laboratory of Epidemiology, Demography, Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Albert Vernon Smith,

  Affiliations Icelandic Heart Association, Kopavogur, Iceland, University of Iceland, Reykjavik, Iceland

  ⨯
• Alan R. Shuldiner,

  Affiliations Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America

  ⨯
• Wendy L. McArdle,

  Affiliation School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

  ⨯
• Mark J. Caulfield,

  Affiliation Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

  ⨯
• Patricia B. Munroe,

  Affiliation Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

  ⨯
• Henrik Grönberg,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

  ⨯
• Yii-Der Ida Chen,

  Affiliations Department of OB/GYN and Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, California, United States of America

  ⨯
• Guo Li,

  Affiliation Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America

  ⨯
• Jacques S. Beckmann,

  Affiliations Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois (CHUV) University Hospital, Lausanne, Switzerland, Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland

  ⨯
• Toby Johnson,

  Affiliations Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland, Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

  ⨯
• Unnur Thorsteinsdottir,

  Affiliations deCODE Genetics, Reykjavik, Iceland, Faculty of Medicine, University of Iceland, Reykjavík, Iceland

  ⨯
• Maris Teder-Laving,

  Affiliation Estonian Genome Center, University of Tartu, Tartu, Estonia

  ⨯
• Kay-Tee Khaw,

  Affiliation Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Nicholas J. Wareham,

  Affiliation MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

  ⨯
• Jing Hua Zhao,

  Affiliation MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

  ⨯
• Najaf Amin,

  Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands

  ⨯
• Ben A. Oostra,

  Affiliations Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands, Centre for Medical Systems Biology & Netherlands Consortium on Healthy Aging, Leiden, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands

  ⨯
• Aldi T. Kraja,

  Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• Michael A. Province,

  Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• L. Adrienne Cupples,

  Affiliation Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America

  ⨯
• Nancy L. Heard-Costa,

  Affiliation Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America

  ⨯
• Jaakko Kaprio,

  Affiliations National Institute for Health and Welfare, Unit for Child and Adolescent Psychiatry, Helsinki, Finland, Finnish Twin Cohort Study, Department of Public Health, University of Helsinki, Helsinki, Finland, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

  ⨯
• Samuli Ripatti,

  Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Department of Chronic Disease Prevention, Unit of Public Health Genomics, Helsinki, Finland

  ⨯
• Ida Surakka,

  Affiliations Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Department of Chronic Disease Prevention, Unit of Public Health Genomics, Helsinki, Finland

  ⨯
• Francis S. Collins,

  Affiliation Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America

  ⨯
• Jouko Saramies,

  Affiliation South Karelia Central Hospital, Lappeenranta, Finland

  ⨯
• Jaakko Tuomilehto,

  Affiliations Red RECAVA Grupo RD06/0014/0015, Hospital Universitario, La Paz, Madrid, Spain, Centre for Vascular Prevention, Danube-University Krems, Krems, Austria, National Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki, Finland, South Ostrobothnia Central Hospital, Seinajoki, Finland

  ⨯
• Antti Jula,

  Affiliation National Institute for Health and Welfare, Department of Chronic Disease Prevention, Population Studies Unit, Turku, Finland

  ⨯
• Veikko Salomaa,

  Affiliation National Institute for Health and Welfare, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, Helsinki, Finland

  ⨯
• Jeanette Erdmann,

  Affiliations Nordic Center of Cardiovascular Research (NCCR), Lübeck, Germany, Universität zu Lübeck, Medizinische Klinik II, Lübeck, Germany

  ⨯
• Christian Hengstenberg,

  Affiliation Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany

  ⨯
• Christina Loley,

  Affiliations Universität zu Lübeck, Medizinische Klinik II, Lübeck, Germany, Deutsches Herzzentrum München and DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany

  ⨯
• Heribert Schunkert,

  Affiliation Deutsches Herzzentrum München and DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany

  ⨯
• Claudia Lamina,

  Affiliation Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria

  ⨯
• H. Erich Wichmann,

  Affiliations Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, and Klinikum Grosshadern, Munich, Germany

  ⨯
• Eva Albrecht,

  Affiliation Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

  ⨯
• Christian Gieger,

  Affiliation Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

  ⨯
• Andrew A. Hicks,

  Affiliation Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano/Bozen, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany

  ⨯
• Åsa Johansson,

  Affiliations Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden, Uppsala Clinical Research Center, Uppsala University Hospital, Uppsala, Sweden

  ⨯
• Peter P. Pramstaller,

  Affiliations Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano/Bozen, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany, Department of Neurology, General Central Hospital, Bolzano, Italy, Department of Neurology, University of Lübeck, Lübeck, Germany

  ⨯
• Sekar Kathiresan,

  Affiliations Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• Elizabeth K. Speliotes,

  Affiliations Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Brenda Penninx,

  Affiliation Department of Psychiatry, University Medical Centre Groningen, Groningen, The Netherlands

  ⨯
• Anna-Liisa Hartikainen,

  Affiliation Department of Clinical Sciences/Obstetrics and Gynecology, University of Oulu, Oulu, Finland

  ⨯
• Marjo-Riitta Jarvelin,

  Affiliations Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, United Kingdom, Institute of Health Sciences, University of Oulu, Oulu, Finland, Biocenter Oulu, University of Oulu, Oulu, Finland, National Institute for Health and Welfare, Oulu, Finland

  ⨯
• Ulf Gyllensten,

  Affiliation Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

  ⨯
• Dorret I. Boomsma,

  Affiliation Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands

  ⨯
• Harry Campbell,

  Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• James F. Wilson,

  Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Stephen J. Chanock,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America

  ⨯
• Martin Farrall,

  Affiliation Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

  ⨯
• Anuj Goel,

  Affiliation Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

  ⨯
• Carolina Medina-Gomez,

  Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

  ⨯
• Fernando Rivadeneira,

  Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

  ⨯
• Karol Estrada,

  Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

  ⨯
• André G. Uitterlinden,

  Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

  ⨯
• Albert Hofman,

  Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands

  ⨯
• M. Carola Zillikens,

  Affiliations Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

  ⨯
• Martin den Heijer,

  Affiliation Department of Internal Medicine, VU University Medical Centre, Amsterdam, The Netherlands

  ⨯
• Lambertus A. Kiemeney,

  Affiliations Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Comprehensive Cancer Center East, Nijmegen, The Netherlands

  ⨯
• Andrea Maschio,

  Affiliation Istituto di Neurogenetica e Neurofarmacologia del CNR, Monserrato, Cagliari, Italy

  ⨯
• Per Hall,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

  ⨯
• Jonathan Tyrer,

  Affiliation Department of Oncology, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Alexander Teumer,

  Affiliation Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany

  ⨯
• Henry Völzke,

  Affiliation Institute for Community Medicine, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany

  ⨯
• Peter Kovacs,

  Affiliation Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany

  ⨯
• Anke Tönjes,

  Affiliations University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany, Department of Medicine, University of Leipzig, Leipzig, Germany

  ⨯
• Massimo Mangino,

  Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

  ⨯
• Tim D. Spector,

  Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

  ⨯
• Caroline Hayward,

  Affiliation MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom

  ⨯
• Igor Rudan,

  Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Alistair S. Hall,

  Affiliation Division of Cardiovascular and Neuronal Remodelling, Multidisciplinary Cardiovascular Research Centre, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom

  ⨯
• Nilesh J. Samani,

  Affiliations Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom, Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester, United Kingdom

  ⨯
• Antony Paul Attwood,

  Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom, Department of Haematology, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Jennifer G. Sambrook,

  Affiliations Department of Haematology, University of Cambridge, Cambridge, United Kingdom, NHS Blood and Transplant, Cambridge Centre, Cambridge, United Kingdom

  ⨯
• Joseph Hung,

  Affiliations School of Medicine and Pharmacology, The University of Western Australia, Nedlands, Western Austrailia, Australia, Busselton Population Medical Research Foundation Inc., Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia

  ⨯
• Lyle J. Palmer,

  Affiliations Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Canada, Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Canada

  ⨯
• Marja-Liisa Lokki,

  Affiliation Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland

  ⨯
• Juha Sinisalo,

  Affiliation Division of Cardiology, Cardiovascular Laboratory, Helsinki University Central Hospital, Helsinki, Finland

  ⨯
• Gabrielle Boucher,

  Affiliation Montreal Heart Institute, Montreal, Quebec, Canada

  ⨯
• Heikki Huikuri,

  Affiliation Institute of Clinical Medicine, Department of Internal Medicine, University of Oulu, Oulu, Finland

  ⨯
• Mattias Lorentzon,

  Affiliation Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

  ⨯
• Claes Ohlsson,

  Affiliation Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

  ⨯
• Niina Eklund,

  Affiliations Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia, National Institute for Health and Welfare, Department of Chronic Disease Prevention, Unit of Public Health Genomics, Helsinki, Finland

  ⨯
• Johan G. Eriksson,

  Affiliations Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Helsinki, Finland, Helsinki University Central Hospital, Unit of General Practice, Helsinki, Finland

  ⨯
• Cristina Barlassina,

  Affiliation University of Milan, Department of Medicine, Surgery and Dentistry, Milano, Italy

  ⨯
• Carlo Rivolta,

  Affiliation Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland

  ⨯
• Ilja M. Nolte,

  Affiliation Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

  ⨯
• Harold Snieder,

  Affiliations Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

  ⨯
• Melanie M. Van der Klauw,

  Affiliations LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Department of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

  ⨯
• Jana V. Van Vliet-Ostaptchouk,

  Affiliations LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Department of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

  ⨯
• Pablo V. Gejman,

  Affiliations University of Chicago, Chicago, Illinois, United States of America, Northshore University Healthsystem, Evanston, Ilinois, United States of America

  ⨯
• Jianxin Shi,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America

  ⨯
• Kevin B. Jacobs,

  Affiliations Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America, Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America

  ⨯
• Zhaoming Wang,

  Affiliations Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America, Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America

  ⨯
• Stephan J. L. Bakker,

  Affiliation Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

  ⨯
• Irene Mateo Leach,

  Affiliation Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

  ⨯
• Gerjan Navis,

  Affiliation Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

  ⨯
• Pim van der Harst,

  Affiliations Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

  ⨯
• Nicholas G. Martin,

  Affiliation Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Queensland, Australia

  ⨯
• Sarah E. Medland,

  Affiliation Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Queensland, Australia

  ⨯
• Grant W. Montgomery,

  Affiliation Molecular Epidemiology Laboratory, Queensland Institute of Medical Research, Queensland, Australia

  ⨯
• Jian Yang,

  Affiliation Queensland Statistical Genetics Laboratory, Queensland Institute of Medical Research, Queensland, Australia

  ⨯
• Daniel I. Chasman,

  Affiliations Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Paul M. Ridker,

  Affiliations Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Lynda M. Rose,

  Affiliation Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  ⨯
• Terho Lehtimäki,

  Affiliation Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Tampere, Finland

  ⨯
• Olli Raitakari,

  Affiliations Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland, The Department of Clinical Physiology, Turku University Hospital, Turku, Finland

  ⨯
• Devin Absher,

  Affiliation Hudson Alpha Institute for Biotechnology, Huntsville, Alabama, United States of America

  ⨯
• Carlos Iribarren,

  Affiliation Division of Research, Kaiser Permanente Northern California, Oakland, California, United States of America

  ⨯
• Hanneke Basart,

  Affiliation Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands

  ⨯
• Kees G. Hovingh,

  Affiliation Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands

  ⨯
• Elina Hyppönen,

  Affiliation Centre For Paediatric Epidemiolgy and Biostatistics/MRC Centre of Epidemiology for Child Health, University College of London Institute of Child Health, London, United Kingdom

  ⨯
• Chris Power,

  Affiliation Centre For Paediatric Epidemiolgy and Biostatistics/MRC Centre of Epidemiology for Child Health, University College of London Institute of Child Health, London, United Kingdom

  ⨯
• Denise Anderson,

  Affiliations Telethon Institute for Child Health Research, West Perth, Western Australia, Australia, Centre for Child Health Research, The University of Western Australia, Perth, Australia

  ⨯
• John P. Beilby,

  Affiliations Busselton Population Medical Research Foundation Inc., Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia, PathWest Laboratory of Western Australia, Department of Molecular Genetics, QEII Medical Centre, Nedlands, Western Australia, Australia, School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia

  ⨯
• Jennie Hui,

  Affiliations Busselton Population Medical Research Foundation Inc., Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia, PathWest Laboratory of Western Australia, Department of Molecular Genetics, QEII Medical Centre, Nedlands, Western Australia, Australia, School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia, School of Population Health, The University of Western Australia, Nedlands, Western Austrailia, Australia

  ⨯
• Jennifer Jolley,

  Affiliation Department of Haematology, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Hendrik Sager,

  Affiliation Medizinische Klinik II, Universität zu Lübeck, Lübeck, Germany

  ⨯
• Stefan R. Bornstein,

  Affiliation Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany

  ⨯
• Peter E. H. Schwarz,

  Affiliation Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany

  ⨯
• Kati Kristiansson,

  Affiliations Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Department of Chronic Disease Prevention, Unit of Public Health Genomics, Helsinki, Finland

  ⨯
• Markus Perola,

  Affiliations Estonian Genome Center, University of Tartu, Tartu, Estonia, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Department of Chronic Disease Prevention, Unit of Public Health Genomics, Helsinki, Finland

  ⨯
• Jaana Lindström,

  Affiliation National Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki, Finland

  ⨯
• Amy J. Swift,

  Affiliation Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America

  ⨯
• Matti Uusitupa,

  Affiliations Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland, Research Unit, Kuopio University Hospital, Kuopio, Finland

  ⨯
• Mustafa Atalay,

  Affiliation Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland

  ⨯
• Timo A. Lakka,

  Affiliations Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland

  ⨯
• Rainer Rauramaa,

  Affiliations Kuopio Research Institute of Exercise Medicine, Kuopio, Finland, Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland

  ⨯
• Jennifer L. Bolton,

  Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Gerry Fowkes,

  Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Ross M. Fraser,

  Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Jackie F. Price,

  Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Krista Fischer,

  Affiliation Estonian Genome Center, University of Tartu, Tartu, Estonia

  ⨯
• Kaarel KrjutÅ¡kov,

  Affiliation Estonian Genome Center, University of Tartu, Tartu, Estonia

  ⨯
• Andres Metspalu,

  Affiliation Estonian Genome Center, University of Tartu, Tartu, Estonia

  ⨯
• Evelin Mihailov,

  Affiliations Estonian Genome Center, University of Tartu, Tartu, Estonia, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

  ⨯
• Claudia Langenberg,

  Affiliations MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom, Department of Epidemiology and Public Health, University College London, London, United Kingdom

  ⨯
• Jian'an Luan,

  Affiliation MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

  ⨯
• Ken K. Ong,

  Affiliations MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom, MRC Unit for Lifelong Health & Ageing, London, United Kingdom

  ⨯
• Peter S. Chines,

  Affiliation Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America

  ⨯
• Sirkka M. Keinanen-Kiukaanniemi,

  Affiliations Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland, Unit of General Practice, Oulu University Hospital, Oulu, Finland

  ⨯
• Timo E. Saaristo,

  Affiliations Finnish Diabetes Association, Tampere, Finland, Pirkanmaa Hospital District, Tampere, Finland

  ⨯
• Sarah Edkins,

  Affiliation Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

  ⨯
• Paul W. Franks,

  Affiliations Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Lund University, Malmö, Sweden, Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Public Health & Clinical Medicine, Umeå University,Umeå, Sweden

  ⨯
• Göran Hallmans,

  Affiliation Department of Public Health & Clinical Medicine, Umeå University,Umeå, Sweden

  ⨯
• Dmitry Shungin,

  Affiliations Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Lund University, Malmö, Sweden, Department of Public Health & Clinical Medicine, Umeå University,Umeå, Sweden, Department of Odontology, Umeå University, Umea, Sweden

  ⨯
• Andrew David Morris,

  Affiliation Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom

  ⨯
• Colin N. A. Palmer,

  Affiliation Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom

  ⨯
• Raimund Erbel,

  Affiliation Clinic of Cardiology, West German Heart Centre, University Hospital of Essen, University Duisburg-Essen, Essen, Germany

  ⨯
• Susanne Moebus,

  Affiliation Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital of Essen, University of Duisburg-Essen, Essen, Germany

  ⨯
• Markus M. Nöthen,

  Affiliations Institute of Human Genetics, University of Bonn, Bonn, Germany, Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany

  ⨯
• Sonali Pechlivanis,

  Affiliation Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital of Essen, University of Duisburg-Essen, Essen, Germany

  ⨯
• Kristian Hveem,

  Affiliation HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway

  ⨯
• Narisu Narisu,

  Affiliation Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America

  ⨯
• Anders Hamsten,

  Affiliation Atherosclerosis Research Unit, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

  ⨯
• Steve E. Humphries,

  Affiliation Cardiovascular Genetics, British Heart Foundation Laboratories, Rayne Building, University College London, London, United Kingdom

  ⨯
• Rona J. Strawbridge,

  Affiliation Atherosclerosis Research Unit, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

  ⨯
• Elena Tremoli,

  Affiliation Department of Pharmacological Sciences, University of Milan, Monzino Cardiology Center, IRCCS, Milan, Italy

  ⨯
• Harald Grallert,

  Affiliation Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

  ⨯
• Barbara Thorand,

  Affiliation Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

  ⨯
• Thomas Illig,

  Affiliations Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, Hannover Unified Biobank, Hannover Medical School, Hannover, Germany

  ⨯
• Wolfgang Koenig,

  Affiliation Department of Internal Medicine II – Cardiology, University of Ulm Medical Center, Ulm, Germany

  ⨯
• Martina Müller-Nurasyid,

  Affiliations Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany, Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany

  ⨯
• Annette Peters,

  Affiliation Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

  ⨯
• Bernhard O. Boehm,

  Affiliation Division of Endocrinology and Diabetes, Department of Medicine, University Hospital, Ulm, Germany

  ⨯
• Marcus E. Kleber,

  Affiliations LURIC Study nonprofit LLC, Freiburg, Germany, Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany

  ⨯
• Winfried März,

  Affiliations Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany, Synlab Academy, Mannheim, Germany

  ⨯
• Bernhard R. Winkelmann,

  Affiliation Cardiology Group, Frankfurt-Sachsenhausen, Germany

  ⨯
• Johanna Kuusisto,

  Affiliation Department of Medicine, University of Kuopio and Kuopio University Hospital, Kuopio, Finland

  ⨯
• Markku Laakso,

  Affiliation Department of Medicine, University of Kuopio and Kuopio University Hospital, Kuopio, Finland

  ⨯
• Dominique Arveiler,

  Affiliation Department of Epidemiology and Public Health, Faculty of Medicine, Strasbourg, France

  ⨯
• Giancarlo Cesana,

  Affiliation Department of Clinical Medicine, University of Milano-Bicocca, Monza, Italy

  ⨯
• Kari Kuulasmaa,

  Affiliation National Institute for Health and Welfare, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, Helsinki, Finland

  ⨯
• Jarmo Virtamo,

  Affiliation National Institute for Health and Welfare, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, Helsinki, Finland

  ⨯
• John W. G. Yarnell,

  Affiliation Centre for Public Health, Queen's University, Belfast, United Kingdom

  ⨯
• Diana Kuh,

  Affiliation MRC Unit for Lifelong Health & Ageing, London, United Kingdom

  ⨯
• Andrew Wong,

  Affiliation MRC Unit for Lifelong Health & Ageing, London, United Kingdom

  ⨯
• Lars Lind,

  Affiliation Department of Medical Sciences, Uppsala University, Akademiska Sjukhuset, Uppsala, Sweden

  ⨯
• Ulf de Faire,

  Affiliation Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

  ⨯
• Bruna Gigante,

  Affiliation Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

  ⨯
• Patrik K. E. Magnusson,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

  ⨯
• Nancy L. Pedersen,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

  ⨯
• George Dedoussis,

  Affiliation Department of Dietetics-Nutrition, Harokopio University, Athens, Greece

  ⨯
• Maria Dimitriou,

  Affiliation Department of Dietetics-Nutrition, Harokopio University, Athens, Greece

  ⨯
• Genovefa Kolovou,

  Affiliation 1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece

  ⨯
• Stavroula Kanoni,

  Affiliation Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

  ⨯
• Kathleen Stirrups,

  Affiliation Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

  ⨯
• Lori L. Bonnycastle,

  Affiliation Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America

  ⨯
• Inger Njølstad,

  Affiliation Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway

  ⨯
• Tom Wilsgaard,

  Affiliation Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway

  ⨯
• Andrea Ganna,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

  ⨯
• Emil Rehnberg,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

  ⨯
• Aroon Hingorani,

  Affiliation Department of Epidemiology and Public Health, University College London, London, United Kingdom

  ⨯
• Mika Kivimaki,

  Affiliation Department of Epidemiology and Public Health, University College London, London, United Kingdom

  ⨯
• Meena Kumari,

  Affiliation Department of Epidemiology and Public Health, University College London, London, United Kingdom

  ⨯
• Themistocles L. Assimes,

  Affiliation Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America

  ⨯
• Inês Barroso,

  Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom, University of Cambridge Metabolic Research Labs, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom

  ⨯
• Michael Boehnke,

  Affiliation Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Ingrid B. Borecki,

  Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

  ⨯
• Panos Deloukas,

  Affiliation Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

  ⨯
• Caroline S. Fox,

  Affiliation Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham Heart Study, Framingham, Massachusetts, United States of America

  ⨯
• Timothy Frayling,

  Affiliation Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom

  ⨯
• Leif C. Groop,

  Affiliation Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Malmö, Sweden

  ⨯
• Talin Haritunians,

  Affiliation Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

  ⨯
• David Hunter,

  Affiliations Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Erik Ingelsson,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

  ⨯
• Robert Kaplan,

  Affiliation Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, United States of America

  ⨯
• Karen L. Mohlke,

  Affiliation Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America

  ⨯
• Jeffrey R. O'Connell,

  Affiliation Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• David Schlessinger,

  Affiliation Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, United States of America

  ⨯
• David P. Strachan,

  Affiliation Division of Community Health Sciences, St George's, University of London, London, United Kingdom

  ⨯
• Kari Stefansson,

  Affiliations deCODE Genetics, Reykjavik, Iceland, Faculty of Medicine, University of Iceland, Reykjavík, Iceland

  ⨯
• Cornelia M. van Duijn,

  Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Center of Medical Systems Biology, Leiden University Medical Center, Leiden, The Netherlands

  ⨯
• Gonçalo R. Abecasis,

  Affiliation Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Mark I. McCarthy,

  Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom, Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom

  ⨯
• Joel N. Hirschhorn,

  Affiliations Divisions of Genetics and Endocrinology and Program in Genomics, Children's Hospital, Boston, Massachusetts, United States of America, Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Lu Qi,

  Affiliations Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America, Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Ruth J. F. Loos ,

  * E-mail: ruth.loos@mssm.edu (RJFL); celi@well.ox.ac.uk (CML); kari_north@unc.edu (KEN); iris.heid@klinik.uni-regensburg.de (IMH)

  ¶These authors supervised this work jointly.

  Affiliations MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom, Genetics of Obesity and Related Metabolic Traits Program,The Charles Bronfman Institute of Personalized Medicine, Child Health and Development Institute, Mount Sinai School of Medicine, New York, New York, United States of America

  ⨯
• Cecilia M. Lindgren ,

  * E-mail: ruth.loos@mssm.edu (RJFL); celi@well.ox.ac.uk (CML); kari_north@unc.edu (KEN); iris.heid@klinik.uni-regensburg.de (IMH)

  ¶These authors supervised this work jointly.

  Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

  ⨯
• Kari E. North ,

  * E-mail: ruth.loos@mssm.edu (RJFL); celi@well.ox.ac.uk (CML); kari_north@unc.edu (KEN); iris.heid@klinik.uni-regensburg.de (IMH)

  ¶These authors supervised this work jointly.

  Affiliation Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  ⨯
•  [ ... ],
• Iris M. Heid

  * E-mail: ruth.loos@mssm.edu (RJFL); celi@well.ox.ac.uk (CML); kari_north@unc.edu (KEN); iris.heid@klinik.uni-regensburg.de (IMH)

  ¶These authors supervised this work jointly.

  Affiliations Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany, Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

  ⨯
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