Duplication and Retention Biases of Essential and Non-Essential Genes Revealed by Systematic Knockdown Analyses

• Shane Woods ,

  Contributed equally to this work with: Shane Woods, Avril Coghlan

  Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom

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• Avril Coghlan ,

  Contributed equally to this work with: Shane Woods, Avril Coghlan

  Affiliations Department of Microbiology, University College Cork, Cork, Ireland, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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• David Rivers ,

  ¶These authors also contributed equally to this work.

  Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom

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• Tobias Warnecke ,

  ¶These authors also contributed equally to this work.

  Affiliation Department of Biology and Biochemistry, University of Bath, Bath, Somerset, United Kingdom

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• Sean J. Jeffries,

  Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom

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• Taejoon Kwon,

  Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom

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• Anthony Rogers,

  Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

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• Laurence D. Hurst ,

  * E-mail: bssldh@bath.ac.uk (LDH); ja219@cam.ac.uk (JA)

  Affiliation Department of Biology and Biochemistry, University of Bath, Bath, Somerset, United Kingdom

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• Julie Ahringer

  * E-mail: bssldh@bath.ac.uk (LDH); ja219@cam.ac.uk (JA)

  Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom

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