MSH3 Polymorphisms and Protein Levels Affect CAG Repeat Instability in Huntington's Disease Mice

• Stéphanie Tomé ,

  Contributed equally to this work with: Stéphanie Tomé, Kevin Manley

  Affiliation Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Kevin Manley ,

  Contributed equally to this work with: Stéphanie Tomé, Kevin Manley

  Affiliations Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Department of Biomedical Sciences, University at Albany, SUNY, Albany, New York, United States of America

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• Jodie P. Simard,

  Affiliation Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada

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• Greg W. Clark,

  Affiliations Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, Campbell Family Institute for Cancer Research, Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada

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• Meghan M. Slean,

  Affiliations Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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• Meera Swami,

  Affiliation Institute of Molecular, Cell, and Systems Biology, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, United Kingdom

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• Peggy F. Shelbourne,

  Affiliation Institute of Molecular, Cell, and Systems Biology, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, United Kingdom

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• Elisabeth R. M. Tillier,

  Affiliations Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, Campbell Family Institute for Cancer Research, Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada

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• Darren G. Monckton,

  Affiliation Institute of Molecular, Cell, and Systems Biology, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, United Kingdom

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• Anne Messer,

  Affiliations Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Department of Biomedical Sciences, University at Albany, SUNY, Albany, New York, United States of America

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• Christopher E. Pearson

  * E-mail: cepearson.sickkids@gmail.com

  Affiliations Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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